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- W1997374803 abstract "To determine the safety and immunogenicity of group B streptococcal (GBS) type III CPS-TT conjugate vaccine in pregnant women.Prospective, randomized (2:1, vaccine:placebo), double-blind, placebo-controlled trial in women at 30-32 weeks' gestation and their infants. Immune responses were measured with IgG-specific ELISA assays; killing of III GBS by 1- and 2-month infant sera was assessed by opsonophagocytosis.Immunization was well-tolerated; maternal and infant outcomes were similar in vaccine and placebo groups. III-TT conjugate elicited good levels of IgG to III CPS that were functionally active against type III GBS through age 2 months.Maternal immunization with GBS CPS-TT conjugates could prevent maternal, neonatal and young infant GBS disease." @default.
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- W1997374803 date "2003-07-28" @default.
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- W1997374803 title "Immunization of pregnant women with group B streptococcal type III capsular polysaccharide-tetanus toxoid conjugate vaccine" @default.
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- W1997374803 doi "https://doi.org/10.1016/s0264-410x(03)00353-0" @default.
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