FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997379747> ?p ?o ?g. }

• W1997379747 endingPage "752" @default.
• W1997379747 startingPage "735" @default.
• W1997379747 abstract "We introduce an approach to protein comparisons in which tertiary-structure information is exploited in the alignment of a protein sequence of known tertiary structure, or an aligned set of sequences of known homologous structures, with one or more sequences. The local tertiary environments of residues in the one or more three-dimensional structures (defined in terms of residue accessibility to solvent, secondary structure and hydrogen bonding) are used to select position-specific amino acid substitution scores and produce a scoring template suitable for aligning sequences or searching sequence data banks. The amino acid substitution score have been accumulated from 72 families of protein structure in which the observed substitutions have been classified according to features of the local structure. Hence, the value attributed to a particular amino acid interchange in the template is not a constant, but is dependent upon the environmental context in which that substitution has occurred. We have used these structural templates to align proteins, as well as to search an amino acid sequence data bank for proteins having a similar fold, Indeed, a database of templates that corresponds to both unique structures and aligned homologous structures from the Brookhaven Protein Data Bank has been produce. A new sequence can be searched against the database of templates in order to identify a similar tertiary fold even if the sequence is not significantly similar to any proteins of known three-dimensional structure." @default.
• W1997379747 created "2016-06-24" @default.
• W1997379747 creator A5001029093 @default.
• W1997379747 creator A5001723208 @default.
• W1997379747 creator A5089062316 @default.
• W1997379747 date "1993-06-01" @default.
• W1997379747 modified "2023-10-09" @default.
• W1997379747 title "Alignment and Searching for Common Protein Folds Using a Data Bank of Structural Templates" @default.
• W1997379747 doi "https://doi.org/10.1006/jmbi.1993.1323" @default.
• W1997379747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8515448" @default.
• W1997379747 hasPublicationYear "1993" @default.
• W1997379747 type Work @default.
• W1997379747 sameAs 1997379747 @default.
• W1997379747 citedByCount "160" @default.
• W1997379747 countsByYear W19973797472013 @default.
• W1997379747 countsByYear W19973797472014 @default.
• W1997379747 countsByYear W19973797472015 @default.
• W1997379747 countsByYear W19973797472017 @default.
• W1997379747 countsByYear W19973797472018 @default.
• W1997379747 countsByYear W19973797472019 @default.
• W1997379747 countsByYear W19973797472020 @default.
• W1997379747 countsByYear W19973797472023 @default.
• W1997379747 crossrefType "journal-article" @default.
• W1997379747 hasAuthorship W1997379747A5001029093 @default.
• W1997379747 hasAuthorship W1997379747A5001723208 @default.
• W1997379747 hasAuthorship W1997379747A5089062316 @default.
• W1997379747 hasConcept C104317684 @default.
• W1997379747 hasConcept C119145174 @default.
• W1997379747 hasConcept C132677234 @default.
• W1997379747 hasConcept C136475424 @default.
• W1997379747 hasConcept C151730666 @default.
• W1997379747 hasConcept C167625842 @default.
• W1997379747 hasConcept C178180057 @default.
• W1997379747 hasConcept C18051474 @default.
• W1997379747 hasConcept C199360897 @default.
• W1997379747 hasConcept C2778112365 @default.
• W1997379747 hasConcept C2779343474 @default.
• W1997379747 hasConcept C2779786304 @default.
• W1997379747 hasConcept C41008148 @default.
• W1997379747 hasConcept C41584329 @default.
• W1997379747 hasConcept C45475804 @default.
• W1997379747 hasConcept C45484198 @default.
• W1997379747 hasConcept C4668613 @default.
• W1997379747 hasConcept C47701112 @default.
• W1997379747 hasConcept C515207424 @default.
• W1997379747 hasConcept C54355233 @default.
• W1997379747 hasConcept C55493867 @default.
• W1997379747 hasConcept C58773245 @default.
• W1997379747 hasConcept C62614982 @default.
• W1997379747 hasConcept C70721500 @default.
• W1997379747 hasConcept C75599170 @default.
• W1997379747 hasConcept C76155785 @default.
• W1997379747 hasConcept C82714645 @default.
• W1997379747 hasConcept C86803240 @default.
• W1997379747 hasConceptScore W1997379747C104317684 @default.
• W1997379747 hasConceptScore W1997379747C119145174 @default.
• W1997379747 hasConceptScore W1997379747C132677234 @default.
• W1997379747 hasConceptScore W1997379747C136475424 @default.
• W1997379747 hasConceptScore W1997379747C151730666 @default.
• W1997379747 hasConceptScore W1997379747C167625842 @default.
• W1997379747 hasConceptScore W1997379747C178180057 @default.
• W1997379747 hasConceptScore W1997379747C18051474 @default.
• W1997379747 hasConceptScore W1997379747C199360897 @default.
• W1997379747 hasConceptScore W1997379747C2778112365 @default.
• W1997379747 hasConceptScore W1997379747C2779343474 @default.
• W1997379747 hasConceptScore W1997379747C2779786304 @default.
• W1997379747 hasConceptScore W1997379747C41008148 @default.
• W1997379747 hasConceptScore W1997379747C41584329 @default.
• W1997379747 hasConceptScore W1997379747C45475804 @default.
• W1997379747 hasConceptScore W1997379747C45484198 @default.
• W1997379747 hasConceptScore W1997379747C4668613 @default.
• W1997379747 hasConceptScore W1997379747C47701112 @default.
• W1997379747 hasConceptScore W1997379747C515207424 @default.
• W1997379747 hasConceptScore W1997379747C54355233 @default.
• W1997379747 hasConceptScore W1997379747C55493867 @default.
• W1997379747 hasConceptScore W1997379747C58773245 @default.
• W1997379747 hasConceptScore W1997379747C62614982 @default.
• W1997379747 hasConceptScore W1997379747C70721500 @default.
• W1997379747 hasConceptScore W1997379747C75599170 @default.
• W1997379747 hasConceptScore W1997379747C76155785 @default.
• W1997379747 hasConceptScore W1997379747C82714645 @default.
• W1997379747 hasConceptScore W1997379747C86803240 @default.
• W1997379747 hasIssue "3" @default.
• W1997379747 hasLocation W19973797471 @default.
• W1997379747 hasLocation W19973797472 @default.
• W1997379747 hasOpenAccess W1997379747 @default.
• W1997379747 hasPrimaryLocation W19973797471 @default.
• W1997379747 hasRelatedWork W1778675583 @default.
• W1997379747 hasRelatedWork W1997379747 @default.
• W1997379747 hasRelatedWork W2051085340 @default.
• W1997379747 hasRelatedWork W2053526761 @default.
• W1997379747 hasRelatedWork W2099254366 @default.
• W1997379747 hasRelatedWork W2106883599 @default.
• W1997379747 hasRelatedWork W2125800162 @default.
• W1997379747 hasRelatedWork W2131204071 @default.
• W1997379747 hasRelatedWork W4285143282 @default.
• W1997379747 hasRelatedWork W4288077714 @default.
• W1997379747 hasVolume "231" @default.

• next