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• W1997399132 abstract "We describe polycatalytic assemblies, comprising one or two streptavidin molecules and two to six attached nucleic acid catalysts (deoxyribozymes), with phosphodiesterase activity. When exposed to a matrix covered at high densities with oligonucleotide substrates, these molecules diffuse through the matrix continuously cleaving the substrate at rates comparable to those of individual catalysts in solution. Rates of diffusion (movement), processivity, and resident times of assemblies can be controlled through the number of catalytic units and the length of substrate/product recognition regions. The assemblies were characterized at the ensemble level using surface plasmon resonance." @default.
• W1997399132 created "2016-06-24" @default.
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• W1997399132 date "2006-09-08" @default.
• W1997399132 modified "2023-09-27" @default.
• W1997399132 title "Behavior of Polycatalytic Assemblies in a Substrate-Displaying Matrix" @default.
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• W1997399132 doi "https://doi.org/10.1021/ja058394n" @default.
• W1997399132 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17002363" @default.
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