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• W1997404722 abstract "We study a generalisation of Moran’s population-genetic model that incorporates density dependence. Rather than assuming fixed population size, we allow the number of individuals to vary stochastically with the same events that change allele number, according to a logistic growth process with density dependent mortality. We analyse the expected time to absorption and fixation in the ‘quasi-neutral’ case: both types have the same carrying capacity, achieved through a trade-off of birth and death rates. Such types would be competitively neutral in a classical, fixed-population Wright–Fisher model. Nonetheless, we find that absorption times are skewed compared to the Wright–Fisher model. The absorption time is longer than the Wright–Fisher prediction when the initial proportion of the type with higher birth rate is large, and shorter when it is small. By contrast, demographic stochasticity has no effect on the fixation or absorption times of truly neutral alleles in a large population. Our calculations provide the first analytic results on hitting times in a two-allele model, when the population size varies stochastically." @default.
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• W1997404722 date "2008-12-01" @default.
• W1997404722 modified "2023-10-01" @default.
• W1997404722 title "Absorption and fixation times for neutral and quasi-neutral populations with density dependence" @default.
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• W1997404722 doi "https://doi.org/10.1016/j.tpb.2008.09.001" @default.
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