FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997415422> ?p ?o ?g. }

• W1997415422 endingPage "64" @default.
• W1997415422 startingPage "59" @default.
• W1997415422 abstract "Individuals with Neurofibromatosis type 1 (NF1) are at risk for developing malignant peripheral nerve sheath tumors (MPNST), which frequently arise in preexisting plexiform neurofibromas (PN). Magnetic resonance imaging (MRI) with volumetric analysis and 18-fluorodeoxyglucose-positron emission tomography (FDG-PET) were utilized to monitor symptomatic nodular lesions.Patients with NF1 and PN on a NCI natural history trial were monitored for total body tumor volume (TTV) using volumetric MRI. FDG-PET was performed in individuals with a nodular well-demarcated lesion ≥3 cm if they were growing, painful, or there was a prior history of MPNST (target lesions). Asymptomatic nodular lesions were evaluated as non-target lesions.Fifteen patients (8m, 7f) median age of 18.3 years (range, 10-45 years) had a single target and non-target (n = 46) nodular lesions identified on MRI. Target lesions arose within (n = 8) or outside (n = 3) a PN, and all but 1 had increased FDG uptake. FDG uptake was increased in non-target lesions but to a lesser degree. FDG uptake in the surrounding PN was low, similar to background activity. Pathologic evaluation performed in 11 patients demonstrated neurofibroma (n = 6), atypical neurofibroma (n = 2) and malignancy (n = 3).Nodular target lesions identified on MRI in individuals with NF1 and PN demonstrate increased FDG uptake similar to MPNST, but may be benign on biopsy. Nodular target lesions may be at greater risk for malignant transformation, but their biologic and clinical behavior has not been well studied. Careful longitudinal evaluation will be required to better understand the malignant potential of these lesions." @default.
• W1997415422 created "2016-06-24" @default.
• W1997415422 creator A5001477884 @default.
• W1997415422 creator A5002810674 @default.
• W1997415422 creator A5020298914 @default.
• W1997415422 creator A5030915747 @default.
• W1997415422 creator A5031777285 @default.
• W1997415422 creator A5050553977 @default.
• W1997415422 creator A5055973779 @default.
• W1997415422 creator A5065281591 @default.
• W1997415422 creator A5068304584 @default.
• W1997415422 creator A5071679104 @default.
• W1997415422 creator A5081724953 @default.
• W1997415422 date "2012-05-29" @default.
• W1997415422 modified "2023-10-16" @default.
• W1997415422 title "18-fluorodeoxyglucose-positron emission tomography (FDG-PET) evaluation of nodular lesions in patients with neurofibromatosis type 1 and plexiform neurofibromas (PN) or malignant peripheral nerve sheath tumors (MPNST)" @default.
• W1997415422 cites W1967830748 @default.
• W1997415422 cites W1968775852 @default.
• W1997415422 cites W1972615559 @default.
• W1997415422 cites W1976510059 @default.
• W1997415422 cites W1987956240 @default.
• W1997415422 cites W1992292239 @default.
• W1997415422 cites W1993574174 @default.
• W1997415422 cites W2010590846 @default.
• W1997415422 cites W2017793525 @default.
• W1997415422 cites W2018996650 @default.
• W1997415422 cites W2044131750 @default.
• W1997415422 cites W2045459584 @default.
• W1997415422 cites W2051528031 @default.
• W1997415422 cites W2060568432 @default.
• W1997415422 cites W2063057728 @default.
• W1997415422 cites W2074320525 @default.
• W1997415422 cites W2074572357 @default.
• W1997415422 cites W2111913639 @default.
• W1997415422 cites W2113286019 @default.
• W1997415422 cites W2137036286 @default.
• W1997415422 cites W2143921230 @default.
• W1997415422 cites W2147361937 @default.
• W1997415422 cites W2154215865 @default.
• W1997415422 cites W4254962459 @default.
• W1997415422 doi "https://doi.org/10.1002/pbc.24212" @default.
• W1997415422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6626667" @default.
• W1997415422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22645095" @default.
• W1997415422 hasPublicationYear "2012" @default.
• W1997415422 type Work @default.
• W1997415422 sameAs 1997415422 @default.
• W1997415422 citedByCount "53" @default.
• W1997415422 countsByYear W19974154222012 @default.
• W1997415422 countsByYear W19974154222013 @default.
• W1997415422 countsByYear W19974154222014 @default.
• W1997415422 countsByYear W19974154222015 @default.
• W1997415422 countsByYear W19974154222016 @default.
• W1997415422 countsByYear W19974154222017 @default.
• W1997415422 countsByYear W19974154222018 @default.
• W1997415422 countsByYear W19974154222019 @default.
• W1997415422 countsByYear W19974154222020 @default.
• W1997415422 countsByYear W19974154222021 @default.
• W1997415422 countsByYear W19974154222022 @default.
• W1997415422 countsByYear W19974154222023 @default.
• W1997415422 crossrefType "journal-article" @default.
• W1997415422 hasAuthorship W1997415422A5001477884 @default.
• W1997415422 hasAuthorship W1997415422A5002810674 @default.
• W1997415422 hasAuthorship W1997415422A5020298914 @default.
• W1997415422 hasAuthorship W1997415422A5030915747 @default.
• W1997415422 hasAuthorship W1997415422A5031777285 @default.
• W1997415422 hasAuthorship W1997415422A5050553977 @default.
• W1997415422 hasAuthorship W1997415422A5055973779 @default.
• W1997415422 hasAuthorship W1997415422A5065281591 @default.
• W1997415422 hasAuthorship W1997415422A5068304584 @default.
• W1997415422 hasAuthorship W1997415422A5071679104 @default.
• W1997415422 hasAuthorship W1997415422A5081724953 @default.
• W1997415422 hasBestOaLocation W19974154222 @default.
• W1997415422 hasConcept C126838900 @default.
• W1997415422 hasConcept C142724271 @default.
• W1997415422 hasConcept C143409427 @default.
• W1997415422 hasConcept C199374082 @default.
• W1997415422 hasConcept C2775842073 @default.
• W1997415422 hasConcept C2775934546 @default.
• W1997415422 hasConcept C2777415128 @default.
• W1997415422 hasConcept C2777831590 @default.
• W1997415422 hasConcept C2777910003 @default.
• W1997415422 hasConcept C2778173781 @default.
• W1997415422 hasConcept C2778984943 @default.
• W1997415422 hasConcept C2779399171 @default.
• W1997415422 hasConcept C2781156865 @default.
• W1997415422 hasConcept C2910357046 @default.
• W1997415422 hasConcept C2989005 @default.
• W1997415422 hasConcept C71924100 @default.
• W1997415422 hasConceptScore W1997415422C126838900 @default.
• W1997415422 hasConceptScore W1997415422C142724271 @default.
• W1997415422 hasConceptScore W1997415422C143409427 @default.
• W1997415422 hasConceptScore W1997415422C199374082 @default.
• W1997415422 hasConceptScore W1997415422C2775842073 @default.
• W1997415422 hasConceptScore W1997415422C2775934546 @default.
• W1997415422 hasConceptScore W1997415422C2777415128 @default.
• W1997415422 hasConceptScore W1997415422C2777831590 @default.
• W1997415422 hasConceptScore W1997415422C2777910003 @default.
• W1997415422 hasConceptScore W1997415422C2778173781 @default.

• next