FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997427230> ?p ?o ?g. }

• W1997427230 endingPage "121" @default.
• W1997427230 startingPage "115" @default.
• W1997427230 abstract "Objectives: Based on the hypothesis that energy impairment may be involved in the pathophysiology of depression, we evaluated the activities of citrate synthase, malate dehydrogenase, succinate dehydrogenase (SDH), mitochondrial respiratory chain complexes I, II, II-III, IV and creatine kinase (CK) in the brain of rats submitted to chronic administration of bupropion. Methods: Animals received daily administration of bupropion dissolved in saline (10 mg/kg, intraperitoneal) at 1.0 ml/kg body weight. The rats received injections once a day for 14 days; control rats received an equivalent volume of saline. Twelve hours after the last administration, the rats were killed by decapitation and brain was rapidly removed and kept on an ice plate. The activities of the enzymes were measured in different brain areas. Results: We observed that the activities of citrate synthase and malate dehydrogenase, mithocondrial respiratory chain complexes I, II-III and IV and CK were not altered after chronic administration of bupropion. However, SDH activity was increased in the prefrontal cortex and cerebellum. In the hippocampus, cerebellum and striatum the activity of complex II was increased after chronic administration of bupropion. Conclusions: Our results demonstrated that bupropion increased some enzymes of brain energy metabolism. These findings are in accordance with other studies which showed that some antidepressants may improve energy metabolism. The present results reinforce the hypothesis that antidepressants modulate brain energy metabolism." @default.
• W1997427230 created "2016-06-24" @default.
• W1997427230 creator A5031113718 @default.
• W1997427230 creator A5038474438 @default.
• W1997427230 creator A5041909785 @default.
• W1997427230 creator A5053113107 @default.
• W1997427230 creator A5060918585 @default.
• W1997427230 creator A5062953785 @default.
• W1997427230 creator A5063284679 @default.
• W1997427230 creator A5067659312 @default.
• W1997427230 creator A5075444218 @default.
• W1997427230 creator A5084364321 @default.
• W1997427230 date "2012-04-01" @default.
• W1997427230 modified "2023-09-24" @default.
• W1997427230 title "Brain energy metabolism is increased by chronic administration of bupropion" @default.
• W1997427230 cites W1451660614 @default.
• W1997427230 cites W1570452496 @default.
• W1997427230 cites W1775749144 @default.
• W1997427230 cites W1804279373 @default.
• W1997427230 cites W1849159432 @default.
• W1997427230 cites W1968000956 @default.
• W1997427230 cites W1970780846 @default.
• W1997427230 cites W1974184864 @default.
• W1997427230 cites W1974776346 @default.
• W1997427230 cites W1977146424 @default.
• W1997427230 cites W1981705617 @default.
• W1997427230 cites W1986790448 @default.
• W1997427230 cites W1994300200 @default.
• W1997427230 cites W1996982207 @default.
• W1997427230 cites W2008246214 @default.
• W1997427230 cites W2011327980 @default.
• W1997427230 cites W2017638772 @default.
• W1997427230 cites W2018556491 @default.
• W1997427230 cites W2019042812 @default.
• W1997427230 cites W2027855941 @default.
• W1997427230 cites W2029135379 @default.
• W1997427230 cites W2032104699 @default.
• W1997427230 cites W2036507871 @default.
• W1997427230 cites W2039045136 @default.
• W1997427230 cites W2044510081 @default.
• W1997427230 cites W2045885275 @default.
• W1997427230 cites W2046809238 @default.
• W1997427230 cites W2049815206 @default.
• W1997427230 cites W2057357882 @default.
• W1997427230 cites W2064183980 @default.
• W1997427230 cites W2064400970 @default.
• W1997427230 cites W2083880873 @default.
• W1997427230 cites W2084190290 @default.
• W1997427230 cites W2084793167 @default.
• W1997427230 cites W2088918288 @default.
• W1997427230 cites W2092440369 @default.
• W1997427230 cites W2140236713 @default.
• W1997427230 cites W2155748853 @default.
• W1997427230 cites W2159061031 @default.
• W1997427230 cites W2160256096 @default.
• W1997427230 cites W2165689677 @default.
• W1997427230 cites W2168530872 @default.
• W1997427230 cites W2178313645 @default.
• W1997427230 cites W2327563727 @default.
• W1997427230 doi "https://doi.org/10.1111/j.1601-5215.2011.00597.x" @default.
• W1997427230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26952953" @default.
• W1997427230 hasPublicationYear "2012" @default.
• W1997427230 type Work @default.
• W1997427230 sameAs 1997427230 @default.
• W1997427230 citedByCount "6" @default.
• W1997427230 countsByYear W19974272302015 @default.
• W1997427230 countsByYear W19974272302019 @default.
• W1997427230 countsByYear W19974272302021 @default.
• W1997427230 countsByYear W19974272302022 @default.
• W1997427230 countsByYear W19974272302023 @default.
• W1997427230 crossrefType "journal-article" @default.
• W1997427230 hasAuthorship W1997427230A5031113718 @default.
• W1997427230 hasAuthorship W1997427230A5038474438 @default.
• W1997427230 hasAuthorship W1997427230A5041909785 @default.
• W1997427230 hasAuthorship W1997427230A5053113107 @default.
• W1997427230 hasAuthorship W1997427230A5060918585 @default.
• W1997427230 hasAuthorship W1997427230A5062953785 @default.
• W1997427230 hasAuthorship W1997427230A5063284679 @default.
• W1997427230 hasAuthorship W1997427230A5067659312 @default.
• W1997427230 hasAuthorship W1997427230A5075444218 @default.
• W1997427230 hasAuthorship W1997427230A5084364321 @default.
• W1997427230 hasConcept C126322002 @default.
• W1997427230 hasConcept C132901563 @default.
• W1997427230 hasConcept C134018914 @default.
• W1997427230 hasConcept C142724271 @default.
• W1997427230 hasConcept C181199279 @default.
• W1997427230 hasConcept C185592680 @default.
• W1997427230 hasConcept C2777318727 @default.
• W1997427230 hasConcept C2777397205 @default.
• W1997427230 hasConcept C2777843972 @default.
• W1997427230 hasConcept C2779908668 @default.
• W1997427230 hasConcept C2780062018 @default.
• W1997427230 hasConcept C2781161787 @default.
• W1997427230 hasConcept C36880943 @default.
• W1997427230 hasConcept C513476851 @default.
• W1997427230 hasConcept C55493867 @default.
• W1997427230 hasConcept C71924100 @default.
• W1997427230 hasConcept C98274493 @default.

• next