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- W1997430893 abstract "To investigate the integrity of the blood-aqueous barrier (BAB) and the blood-retinal barrier (BRB) in diabetic patients with clinically significant macular edema (CSME).The rate constant (Kd(F)) of the BAB and the permeability of the blood-retinal barrier for non-protein bound fluorescein were determined simultaneously by fluorometry. Results were analysed pairwise in diabetic patients (n = 25) with CSME in one eye and without CSME in the other eye.Kd(F) for the eyes with CSME was significantly increased compared to eyes without CSME (444. 10(-6) min( -1) and 387. 10(-6) min(-1) respectively, p = 0.01). The passive permeability of the BRB was also significantly increased in CSME (5.7 nm/sec and 3.5 nm/sec respectively, p = 0.009, n = 19).Both the rate constant of the BAB and the BRB permeability were significantly increased in CSME indicating that eye-specific factors are common for both barriers in diabetic patients with CSME." @default.
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- W1997430893 date "2003-01-01" @default.
- W1997430893 modified "2023-09-25" @default.
- W1997430893 title "Fluorescein transport through the blood-aqueous and blood-retinal barriers in diabetic macular edema" @default.
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- W1997430893 doi "https://doi.org/10.1076/ceyr.27.4.247.16596" @default.
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