Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997433105> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1997433105 endingPage "90" @default.
- W1997433105 startingPage "85" @default.
- W1997433105 abstract "Spotting and bleeding are among the most common side effects associated with oral contraceptive (OC) use and their occurrence is a prime determinant of whether a new user will continue to use OCs. Desogestrel and gestodene are two new progestins that were developed in part to minimize the occurrence of these side effects. Assessing the effect of these progestins is difficult, however, in part because their effects may be subtle, requiring a large sample size and possibly being overshadowed by other factors. To address these issues, we analyzed data from two comparative multicenter clinical trials that included 15,421 cycles among 2767 women. One study compared 75 μg gestodene + 30 μg ethinyl estradiol (EE) with 150 μg desogestrel + 30 μg EE, the other compared the same gestodene preparation with 150 μg desogestrel + 20 μg EE. Both studies found a higher risk of spotting or bleeding in all cycles among users of the desogestrel-containing preparation, with the differences ranging between 20% and 70% higher for the first study and 40% and 140% in the second. These differences were statistically significant in four of six cycles in each study and persisted after controlling for consistency and recency of OC use as well as smoking. After pooling the data and controlling for estrogen dose, the desogestrel-containing preparation was significantly associated with more frequent spotting or bleeding in five of six cycles. Smoking and consistency and recency of OC use were also independent predictors of spotting or bleeding." @default.
- W1997433105 created "2016-06-24" @default.
- W1997433105 creator A5011847156 @default.
- W1997433105 creator A5015633060 @default.
- W1997433105 creator A5025490498 @default.
- W1997433105 date "1996-02-01" @default.
- W1997433105 modified "2023-10-16" @default.
- W1997433105 title "The effect of desogestrel, gestodene, and other factors on spotting and bleeding" @default.
- W1997433105 cites W1997013992 @default.
- W1997433105 cites W2026730705 @default.
- W1997433105 cites W2042830508 @default.
- W1997433105 cites W2046847066 @default.
- W1997433105 cites W2089261643 @default.
- W1997433105 cites W2168024869 @default.
- W1997433105 cites W4236725586 @default.
- W1997433105 cites W47794394 @default.
- W1997433105 cites W57011204 @default.
- W1997433105 doi "https://doi.org/10.1016/0010-7824(95)00270-7" @default.
- W1997433105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8838484" @default.
- W1997433105 hasPublicationYear "1996" @default.
- W1997433105 type Work @default.
- W1997433105 sameAs 1997433105 @default.
- W1997433105 citedByCount "37" @default.
- W1997433105 countsByYear W19974331052013 @default.
- W1997433105 countsByYear W19974331052014 @default.
- W1997433105 countsByYear W19974331052015 @default.
- W1997433105 countsByYear W19974331052016 @default.
- W1997433105 countsByYear W19974331052017 @default.
- W1997433105 countsByYear W19974331052022 @default.
- W1997433105 crossrefType "journal-article" @default.
- W1997433105 hasAuthorship W1997433105A5011847156 @default.
- W1997433105 hasAuthorship W1997433105A5015633060 @default.
- W1997433105 hasAuthorship W1997433105A5025490498 @default.
- W1997433105 hasConcept C120665830 @default.
- W1997433105 hasConcept C121332964 @default.
- W1997433105 hasConcept C126322002 @default.
- W1997433105 hasConcept C2778239997 @default.
- W1997433105 hasConcept C2779076696 @default.
- W1997433105 hasConcept C2779441745 @default.
- W1997433105 hasConcept C2779506182 @default.
- W1997433105 hasConcept C2908647359 @default.
- W1997433105 hasConcept C29456083 @default.
- W1997433105 hasConcept C2986817661 @default.
- W1997433105 hasConcept C42407357 @default.
- W1997433105 hasConcept C71924100 @default.
- W1997433105 hasConcept C99454951 @default.
- W1997433105 hasConceptScore W1997433105C120665830 @default.
- W1997433105 hasConceptScore W1997433105C121332964 @default.
- W1997433105 hasConceptScore W1997433105C126322002 @default.
- W1997433105 hasConceptScore W1997433105C2778239997 @default.
- W1997433105 hasConceptScore W1997433105C2779076696 @default.
- W1997433105 hasConceptScore W1997433105C2779441745 @default.
- W1997433105 hasConceptScore W1997433105C2779506182 @default.
- W1997433105 hasConceptScore W1997433105C2908647359 @default.
- W1997433105 hasConceptScore W1997433105C29456083 @default.
- W1997433105 hasConceptScore W1997433105C2986817661 @default.
- W1997433105 hasConceptScore W1997433105C42407357 @default.
- W1997433105 hasConceptScore W1997433105C71924100 @default.
- W1997433105 hasConceptScore W1997433105C99454951 @default.
- W1997433105 hasIssue "2" @default.
- W1997433105 hasLocation W19974331051 @default.
- W1997433105 hasLocation W19974331052 @default.
- W1997433105 hasOpenAccess W1997433105 @default.
- W1997433105 hasPrimaryLocation W19974331051 @default.
- W1997433105 hasRelatedWork W1776852909 @default.
- W1997433105 hasRelatedWork W1969180133 @default.
- W1997433105 hasRelatedWork W1984706617 @default.
- W1997433105 hasRelatedWork W2032238979 @default.
- W1997433105 hasRelatedWork W2052111637 @default.
- W1997433105 hasRelatedWork W2076996455 @default.
- W1997433105 hasRelatedWork W4237935771 @default.
- W1997433105 hasRelatedWork W4298369989 @default.
- W1997433105 hasRelatedWork W2290004098 @default.
- W1997433105 hasRelatedWork W2616979326 @default.
- W1997433105 hasVolume "53" @default.
- W1997433105 isParatext "false" @default.
- W1997433105 isRetracted "false" @default.
- W1997433105 magId "1997433105" @default.
- W1997433105 workType "article" @default.