FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997433483> ?p ?o ?g. }

• W1997433483 endingPage "84" @default.
• W1997433483 startingPage "79" @default.
• W1997433483 abstract "BACKGROUND: Detecting small‐volume aspirations of gastric contents is an important but difficult task. A potentially useful method for this purpose is assaying tracheal secretions for pepsin, an expected constituent of gastric juice. METHODS: A 2‐group experimental design was used. The primary subjects were 161 experimental and 21 control New Zealand white rabbits; 161 acutely ill humans provided the gastric juice used in the project. The animals were anesthetized before being intubated and mechanically ventilated. Three separate boluses of human gastric juice mixed with dye‐stained enteral formula were instilled into the experimental animals' tracheas; the 21 control animals received only 0.9% sodium chloride solution. At the beginning of each experiment, 0.4 mL/kg of the substance was infused over a 30‐minute period; the infusion was then stopped and 90 minutes were allowed to elapse before endotracheal suctioning was performed. This procedure was repeated at hour 2 and hour 4. After completion of the multiple aspiration portion of the study, 23 additional animals were subjected to a single aspiration of 0.4 mL/kg of a mixture of human gastric juice and dye‐stained enteral formula; secretions were obtained at 2 hours, 4 hours, and 6 hours. An immunoassay was used to test for pepsin in all of the tracheal secretions. RESULTS: In the 3‐aspiration group, pepsin was found in all of the secretions from 92.5% (149/161) of the experimental animals; in contrast, no pepsin was found in any of the secretions from the 20 control animals. In the single‐aspiration group, pepsin was found in all of the tracheal secretions from the 23 animals at 2 hours and 4 hours and 21 of the 23 animals at 6 hours. CONCLUSIONS: The immunoassay used in this animal model study was able to detect pepsin in >90% of the experimental animals' tracheal secretions after multiple or single forced aspirations of gastric juice. The extent to which pepsin can be detected in the tracheal secretions of acutely ill tube‐fed humans requires investigation, as does the extent to which clinical outcomes are affected by pepsin‐positive tracheal secretions." @default.
• W1997433483 created "2016-06-24" @default.
• W1997433483 creator A5010267805 @default.
• W1997433483 creator A5031100742 @default.
• W1997433483 creator A5031110357 @default.
• W1997433483 creator A5063316778 @default.
• W1997433483 creator A5079146733 @default.
• W1997433483 creator A5081709926 @default.
• W1997433483 date "2004-03-01" @default.
• W1997433483 modified "2023-09-30" @default.
• W1997433483 title "Detection of pepsin in tracheal secretions after forced small-volume aspirations of gastric juice" @default.
• W1997433483 cites W1834471490 @default.
• W1997433483 cites W2001949567 @default.
• W1997433483 cites W2006152016 @default.
• W1997433483 cites W2018858172 @default.
• W1997433483 cites W2030097417 @default.
• W1997433483 cites W2051857059 @default.
• W1997433483 cites W2054076896 @default.
• W1997433483 cites W2073634136 @default.
• W1997433483 cites W2074863116 @default.
• W1997433483 cites W2114329602 @default.
• W1997433483 cites W2121446842 @default.
• W1997433483 cites W2123648294 @default.
• W1997433483 cites W2171429631 @default.
• W1997433483 doi "https://doi.org/10.1177/014860710402800279" @default.
• W1997433483 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2642973" @default.
• W1997433483 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15080601" @default.
• W1997433483 hasPublicationYear "2004" @default.
• W1997433483 type Work @default.
• W1997433483 sameAs 1997433483 @default.
• W1997433483 citedByCount "43" @default.
• W1997433483 countsByYear W19974334832012 @default.
• W1997433483 countsByYear W19974334832013 @default.
• W1997433483 countsByYear W19974334832014 @default.
• W1997433483 countsByYear W19974334832015 @default.
• W1997433483 countsByYear W19974334832016 @default.
• W1997433483 countsByYear W19974334832017 @default.
• W1997433483 countsByYear W19974334832020 @default.
• W1997433483 countsByYear W19974334832021 @default.
• W1997433483 countsByYear W19974334832022 @default.
• W1997433483 crossrefType "journal-article" @default.
• W1997433483 hasAuthorship W1997433483A5010267805 @default.
• W1997433483 hasAuthorship W1997433483A5031100742 @default.
• W1997433483 hasAuthorship W1997433483A5031110357 @default.
• W1997433483 hasAuthorship W1997433483A5063316778 @default.
• W1997433483 hasAuthorship W1997433483A5079146733 @default.
• W1997433483 hasAuthorship W1997433483A5081709926 @default.
• W1997433483 hasBestOaLocation W19974334832 @default.
• W1997433483 hasConcept C126322002 @default.
• W1997433483 hasConcept C16311235 @default.
• W1997433483 hasConcept C181199279 @default.
• W1997433483 hasConcept C185592680 @default.
• W1997433483 hasConcept C2777963132 @default.
• W1997433483 hasConcept C2779422922 @default.
• W1997433483 hasConcept C2909667141 @default.
• W1997433483 hasConcept C42219234 @default.
• W1997433483 hasConcept C44315111 @default.
• W1997433483 hasConcept C55493867 @default.
• W1997433483 hasConcept C71924100 @default.
• W1997433483 hasConcept C78722104 @default.
• W1997433483 hasConcept C90924648 @default.
• W1997433483 hasConceptScore W1997433483C126322002 @default.
• W1997433483 hasConceptScore W1997433483C16311235 @default.
• W1997433483 hasConceptScore W1997433483C181199279 @default.
• W1997433483 hasConceptScore W1997433483C185592680 @default.
• W1997433483 hasConceptScore W1997433483C2777963132 @default.
• W1997433483 hasConceptScore W1997433483C2779422922 @default.
• W1997433483 hasConceptScore W1997433483C2909667141 @default.
• W1997433483 hasConceptScore W1997433483C42219234 @default.
• W1997433483 hasConceptScore W1997433483C44315111 @default.
• W1997433483 hasConceptScore W1997433483C55493867 @default.
• W1997433483 hasConceptScore W1997433483C71924100 @default.
• W1997433483 hasConceptScore W1997433483C78722104 @default.
• W1997433483 hasConceptScore W1997433483C90924648 @default.
• W1997433483 hasIssue "2" @default.
• W1997433483 hasLocation W19974334831 @default.
• W1997433483 hasLocation W19974334832 @default.
• W1997433483 hasLocation W19974334833 @default.
• W1997433483 hasLocation W19974334834 @default.
• W1997433483 hasOpenAccess W1997433483 @default.
• W1997433483 hasPrimaryLocation W19974334831 @default.
• W1997433483 hasRelatedWork W196353441 @default.
• W1997433483 hasRelatedWork W1971215789 @default.
• W1997433483 hasRelatedWork W1989233164 @default.
• W1997433483 hasRelatedWork W1995096517 @default.
• W1997433483 hasRelatedWork W1997433483 @default.
• W1997433483 hasRelatedWork W2287018356 @default.
• W1997433483 hasRelatedWork W2415925009 @default.
• W1997433483 hasRelatedWork W2440656931 @default.
• W1997433483 hasRelatedWork W2981155413 @default.
• W1997433483 hasRelatedWork W4386221370 @default.
• W1997433483 hasVolume "28" @default.
• W1997433483 isParatext "false" @default.
• W1997433483 isRetracted "false" @default.
• W1997433483 magId "1997433483" @default.
• W1997433483 workType "article" @default.