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• W1997465401 abstract "The cellular site of synthesis of vesicular stomatitis virus was studied through the use of actinomyciu D, mitomycin C, ultraviolet light irradiation, immunofluorescence and electron microscopy. Following the various treatments, virus infectivity was assayed by tube titrations and plaque assays. Chick embryo cells, African green monkey kidney cells and the WI-38 strain of human embryonic lung cells were used in the study. The results obtained indicate that the replication of VSV is not DNA dependent and that the replicative process takes place in the cytoplasm. This is supported by the results of immunofluorescent tracing and electron microscopy. In the former case no nuclear localization of viral antigen was demonstrable throughout the replicative cycle of the virus. Electron microscopy also revealed that virus particles were located exclusively in the cytoplasm of both antibiotic treated infected cells as well as in infected but untreated cells. The virus particles in antibiotic treated cells appeared normal and in larger number than in untreated cultures." @default.
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• W1997465401 date "1968-03-01" @default.
• W1997465401 modified "2023-10-16" @default.
• W1997465401 title "Studies on the site of replication of vesicular stomatitis virus" @default.
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• W1997465401 doi "https://doi.org/10.1007/bf01242900" @default.
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