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- W1997465714 abstract "Although women may have an increased risk of complications following interventions, the etiology of this gender-related effect remains uncertain. While oversizing of angioplasty balloons is associated with increased complications, no angiographic data have demonstrated inappropriate balloon sizing in women. We performed intravascular ultrasound and quantitative angiography in 124 patients (101 males, 23 females) before and after coronary balloon angioplasty. In 51 patients, balloon angioplasty was the primary therapy, while in 73, balloon dilatation was performed as an adjunct to rotational or directional atherectomy. Separate core laboratories, blinded to outcome, measured angiographic and ultrasound dimensions in reference segments and target lesions. Results Men Women p value Angio Reference (mm) 3.50 3.29 NS Ultrasound Reference (mm) 3.37 2.85 0.001 Balloon Size (mm) 3.48 3.27 0.10 Balloon/Angio Ratio 1.00 1.02 NS Balloon/Ultrasound Ratio 1.06 1.17 0.05 These important differences in the ratio of balloon to ultrasound vessel diameter are partially explained by a greater plaque burden at reference sites in women (ultrasound area reduction of 43.7% vs. 37.6%). Although balloons were appropriately sized in women when compared to angiographic diameter, significant oversizing of balloon catheters in women was apparent when compared to ultrasound reference segment dimensions. These findings have important clinical implications for coronary interventions in women." @default.
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- W1997465714 date "1995-02-01" @default.
- W1997465714 modified "2023-09-25" @default.
- W1997465714 title "918-21 Intravascular Ultrasound Evidence of Significant Oversizing of Angioplasty Balloons in Female Patients" @default.
- W1997465714 doi "https://doi.org/10.1016/0735-1097(95)91845-o" @default.
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