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- W1997478807 abstract "Chronic liver disease and hepatocellular carcinoma associated with chronic hepatitis B virus (HBV) infection are among the most serious human health problems in highly endemic regions. Although, effective vaccines against HBV have been available for many years, over 350 million people still remain persistently infected with HBV. Current therapies fail to provide long-term control of viral replication in most patients. Viral persistence has been associated with a defect in the development of HBV-specific cell-mediated immunity. Vaccine-based strategies to boost or to broaden the weak virus-specific T cell response of patients with chronic hepatitis B are proposed as a means of terminating this persistent infection." @default.
- W1997478807 created "2016-06-24" @default.
- W1997478807 creator A5033281553 @default.
- W1997478807 date "2002-12-01" @default.
- W1997478807 modified "2023-09-27" @default.
- W1997478807 title "Towards immunotherapy for chronic hepatitis B virus infections" @default.
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- W1997478807 doi "https://doi.org/10.1016/s0264-410x(02)00393-6" @default.
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