FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997510140> ?p ?o ?g. }

• W1997510140 endingPage "251" @default.
• W1997510140 startingPage "245" @default.
• W1997510140 abstract "Eight-week-old, female Wistar fatty rats and their lean littermates were given a 30% sucrose solution in addition to a laboratory chow diet and water for 7 weeks. The fatty rats were hyperinsulinemic and hyperlipidemic, but normoglycemic when they drank only water. The hepatic activities of insulin-inducible glucokinase (GK), pyruvate kinase (PK), and malic enzyme (ME) were higher in the fatty rats than in the lean rats, whereas the insulin-suppressible glucose-6-phosphatase (G6Pase) activity was similar in both types of rats, indicating the normal response of hepatic enzymes to hyperinsulinemia in the fatty rats. When they drank the sucrose solution, the fatty rats, but not the lean rats, developed hyperglycemia over 200 mg/dl. Plasma insulin and triglyceride concentrations increased in both types of rats. Although the hepatic activities of GK, PK, and ME in the lean rats, and PK and ME in the fatty rats increased in response to the increase in plasma insulin, GK activity decreased in the fatty rats. On the other hand, G6Pase activity increased in both types of rats. As a result, the G6Pase/GK ratio, which may reflect net glucose handling in the liver, increased twofold in the fatty rats, but did not alter in the lean rats. From these findings, we conclude that sucrose ingestion induces an increase in hepatic glucose production through derangement of the hepatic enzyme profile and that the resultant decrease in hepatic glucose handling may be one of the pathogenic factors participating in the development of hyperglycemia in Wistar fatty rats." @default.
• W1997510140 created "2016-06-24" @default.
• W1997510140 creator A5007671862 @default.
• W1997510140 creator A5053123676 @default.
• W1997510140 creator A5059961219 @default.
• W1997510140 date "1989-01-01" @default.
• W1997510140 modified "2023-10-16" @default.
• W1997510140 title "Derangement in Hepatic Enzymes Caused by Sucrose-Drinking and Its Implication for the Development of Hyperglycemia in Female Wistar Fatty Rats." @default.
• W1997510140 cites W1513077899 @default.
• W1997510140 cites W1775749144 @default.
• W1997510140 cites W1817795745 @default.
• W1997510140 cites W1964476964 @default.
• W1997510140 cites W1965306011 @default.
• W1997510140 cites W2014595943 @default.
• W1997510140 cites W2014822390 @default.
• W1997510140 cites W2021259357 @default.
• W1997510140 cites W2021687076 @default.
• W1997510140 cites W2027947443 @default.
• W1997510140 cites W2044288005 @default.
• W1997510140 cites W2058847402 @default.
• W1997510140 cites W2062299625 @default.
• W1997510140 cites W2066547864 @default.
• W1997510140 cites W2075146090 @default.
• W1997510140 cites W2083544956 @default.
• W1997510140 cites W2091955024 @default.
• W1997510140 cites W2094454669 @default.
• W1997510140 cites W2106606181 @default.
• W1997510140 cites W21693120 @default.
• W1997510140 cites W2182528029 @default.
• W1997510140 cites W2231694041 @default.
• W1997510140 cites W2336532500 @default.
• W1997510140 cites W2416868414 @default.
• W1997510140 doi "https://doi.org/10.1507/endocrj1954.36.245" @default.
• W1997510140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2673749" @default.
• W1997510140 hasPublicationYear "1989" @default.
• W1997510140 type Work @default.
• W1997510140 sameAs 1997510140 @default.
• W1997510140 citedByCount "11" @default.
• W1997510140 countsByYear W19975101402016 @default.
• W1997510140 crossrefType "journal-article" @default.
• W1997510140 hasAuthorship W1997510140A5007671862 @default.
• W1997510140 hasAuthorship W1997510140A5053123676 @default.
• W1997510140 hasAuthorship W1997510140A5059961219 @default.
• W1997510140 hasBestOaLocation W19975101401 @default.
• W1997510140 hasConcept C126322002 @default.
• W1997510140 hasConcept C134018914 @default.
• W1997510140 hasConcept C181199279 @default.
• W1997510140 hasConcept C185592680 @default.
• W1997510140 hasConcept C2776317432 @default.
• W1997510140 hasConcept C2776941171 @default.
• W1997510140 hasConcept C2777391703 @default.
• W1997510140 hasConcept C2778163477 @default.
• W1997510140 hasConcept C2778597767 @default.
• W1997510140 hasConcept C2778772119 @default.
• W1997510140 hasConcept C2778913445 @default.
• W1997510140 hasConcept C2778957662 @default.
• W1997510140 hasConcept C2779134260 @default.
• W1997510140 hasConcept C2779306644 @default.
• W1997510140 hasConcept C2780988686 @default.
• W1997510140 hasConcept C543025807 @default.
• W1997510140 hasConcept C55493867 @default.
• W1997510140 hasConcept C71924100 @default.
• W1997510140 hasConcept C86803240 @default.
• W1997510140 hasConcept C98335778 @default.
• W1997510140 hasConceptScore W1997510140C126322002 @default.
• W1997510140 hasConceptScore W1997510140C134018914 @default.
• W1997510140 hasConceptScore W1997510140C181199279 @default.
• W1997510140 hasConceptScore W1997510140C185592680 @default.
• W1997510140 hasConceptScore W1997510140C2776317432 @default.
• W1997510140 hasConceptScore W1997510140C2776941171 @default.
• W1997510140 hasConceptScore W1997510140C2777391703 @default.
• W1997510140 hasConceptScore W1997510140C2778163477 @default.
• W1997510140 hasConceptScore W1997510140C2778597767 @default.
• W1997510140 hasConceptScore W1997510140C2778772119 @default.
• W1997510140 hasConceptScore W1997510140C2778913445 @default.
• W1997510140 hasConceptScore W1997510140C2778957662 @default.
• W1997510140 hasConceptScore W1997510140C2779134260 @default.
• W1997510140 hasConceptScore W1997510140C2779306644 @default.
• W1997510140 hasConceptScore W1997510140C2780988686 @default.
• W1997510140 hasConceptScore W1997510140C543025807 @default.
• W1997510140 hasConceptScore W1997510140C55493867 @default.
• W1997510140 hasConceptScore W1997510140C71924100 @default.
• W1997510140 hasConceptScore W1997510140C86803240 @default.
• W1997510140 hasConceptScore W1997510140C98335778 @default.
• W1997510140 hasIssue "2" @default.
• W1997510140 hasLocation W19975101401 @default.
• W1997510140 hasLocation W19975101402 @default.
• W1997510140 hasOpenAccess W1997510140 @default.
• W1997510140 hasPrimaryLocation W19975101401 @default.
• W1997510140 hasRelatedWork W1969204490 @default.
• W1997510140 hasRelatedWork W1997510140 @default.
• W1997510140 hasRelatedWork W2025603556 @default.
• W1997510140 hasRelatedWork W2027947443 @default.
• W1997510140 hasRelatedWork W2033840628 @default.
• W1997510140 hasRelatedWork W2131745238 @default.
• W1997510140 hasRelatedWork W2153742172 @default.
• W1997510140 hasRelatedWork W2154511047 @default.
• W1997510140 hasRelatedWork W2410167096 @default.

• next