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• W1997515239 abstract "The authors have characterized frontal cortical tau protein in cognitively intact (4) and cognitively impaired (ALSci, 4) ALS patients and compared it with control (2) or Alzheimer disease (AD, 1)- derived tau. The authors observed expression of both 3R and 4R tau isoforms; increased insoluble tau protein; phosphatase resistance; and hyperphosphorylation at T175, S208, and S210. Soluble tau from both AD and ALSci was also phosphorylated at S237. Tau hyperphosphorylation is associated with ALS." @default.
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• W1997515239 date "2006-06-12" @default.
• W1997515239 modified "2023-09-30" @default.
• W1997515239 title "Tau protein hyperphosphorylation in sporadic ALS with cognitive impairment" @default.
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• W1997515239 doi "https://doi.org/10.1212/01.wnl.0000218161.15834.db" @default.
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