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• W1997517495 abstract "Nanodiscs are protein-lipid particles that furnish a nanometer-sized membrane environment for the investigation of membrane proteins. Nanodiscs assemble spontaneously upon the removal of cholate from an initial mixture of cholate, lipids, and engineered amphipathic proteins. A combined experimental-computational approach is applied here to study the disassembly of nanodiscs through the addition of cholate to preformed particles. For this purpose, small-angle X-ray scattering experiments and coarse-grained molecular dynamics simulations were performed and compared. The study offers a detailed view of nanodisc dynamics." @default.
• W1997517495 created "2016-06-24" @default.
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• W1997517495 date "2007-05-16" @default.
• W1997517495 modified "2023-09-30" @default.
• W1997517495 title "Disassembly of Nanodiscs with Cholate" @default.
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• W1997517495 doi "https://doi.org/10.1021/nl0706906" @default.
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