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• W1997533013 abstract "Rutin (compound 5) and some compounds (compounds 1–4 and 6) were isolated from Artemisia princeps Pamp (A. princeps Pamp.) and a series of novel rutin derivatives containing 1,4-pentadien-3-one moiety were designed and synthesized. The target compounds were characterized by proton nuclear magnetic resonance spectroscopy (1H NMR), carbon nuclear magnetic resonance spectroscopy (13C NMR), and ESI-MS. Bioassay results indicated that some of the compounds showed good to excellent antiviral activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) at 500 μg/mL in vivo. The 50% effective concentrations (EC50) of the compound 7r against CMV was 394.78 μg/mL, which was better than that of Ningnanmycin (432.22 μg/mL). These results indicated that novel rutin derivatives containing 1,4-pentadien-3-one moiety can effectively control CMV." @default.
• W1997533013 created "2016-06-24" @default.
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• W1997533013 date "2015-03-01" @default.
• W1997533013 modified "2023-10-16" @default.
• W1997533013 title "Design, synthesis, and antiviral activity of novel rutin derivatives containing 1, 4-pentadien-3-one moiety" @default.
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• W1997533013 doi "https://doi.org/10.1016/j.ejmech.2015.01.017" @default.
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