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• W1997573719 endingPage "215" @default.
• W1997573719 startingPage "215" @default.
• W1997573719 abstract "The number of papers about decavanadate has doubled in the past decade. In the present review, new insights into decavanadate biochemistry, cell biology, and antidiabetic and antitumor activities are described. Decameric vanadate species (V(10)) clearly differs from monomeric vanadate (V(1)), and affects differently calcium pumps, and structure and function of myosin and actin. Only decavanadate inhibits calcium accumulation by calcium pump ATPase, and strongly inhibits actomyosin ATPase activity (IC(50) = 1.4 μmol/L, V(10)), whereas no such effects are detected with V(1) up to 150 μmol/L; prevents actin polymerization (IC(50) of 68 μmol/L, whereas no effects detected with up to 2 mmol/L V(1)); and interacts with actin in a way that induces cysteine oxidation and vanadate reduction to vanadyl. Moreover, in vivo decavanadate toxicity studies have revealed that acute exposure to polyoxovanadate induces different changes in antioxidant enzymes and oxidative stress parameters, in comparison with vanadate. In vitro studies have clearly demonstrated that mitochondrial oxygen consumption is strongly affected by decavanadate (IC(50), 0.1 μmol/L); perhaps the most relevant biological effect. Finally, decavanadate (100 μmol/L) increases rat adipocyte glucose accumulation more potently than several vanadium complexes. Preliminary studies suggest that decavanadate does not have similar effects in human adipocytes. Although decavanadate can be a useful biochemical tool, further studies must be carried out before it can be confirmed that decavanadate and its complexes can be used as anticancer or antidiabetic agents." @default.
• W1997573719 created "2016-06-24" @default.
• W1997573719 creator A5043386771 @default.
• W1997573719 date "2011-01-01" @default.
• W1997573719 modified "2023-10-16" @default.
• W1997573719 title "Recent perspectives into biochemistry of decavanadate" @default.
• W1997573719 cites W1484955319 @default.
• W1997573719 cites W1539622248 @default.
• W1997573719 cites W1574349607 @default.
• W1997573719 cites W1965820862 @default.
• W1997573719 cites W1966044395 @default.
• W1997573719 cites W1969713728 @default.
• W1997573719 cites W1970401962 @default.
• W1997573719 cites W1973495335 @default.
• W1997573719 cites W1973837961 @default.
• W1997573719 cites W1976557087 @default.
• W1997573719 cites W1980990284 @default.
• W1997573719 cites W1987015966 @default.
• W1997573719 cites W1989381085 @default.
• W1997573719 cites W1991212037 @default.
• W1997573719 cites W1994485344 @default.
• W1997573719 cites W1997027039 @default.
• W1997573719 cites W1998331318 @default.
• W1997573719 cites W2004986030 @default.
• W1997573719 cites W2009845851 @default.
• W1997573719 cites W2010583888 @default.
• W1997573719 cites W2013256843 @default.
• W1997573719 cites W2019749529 @default.
• W1997573719 cites W2021123087 @default.
• W1997573719 cites W2023735749 @default.
• W1997573719 cites W2024719340 @default.
• W1997573719 cites W2027935944 @default.
• W1997573719 cites W2029009174 @default.
• W1997573719 cites W2029787796 @default.
• W1997573719 cites W2031245816 @default.
• W1997573719 cites W2032157487 @default.
• W1997573719 cites W2037443162 @default.
• W1997573719 cites W2038314508 @default.
• W1997573719 cites W2040749749 @default.
• W1997573719 cites W2041790399 @default.
• W1997573719 cites W2043740662 @default.
• W1997573719 cites W2045886744 @default.
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• W1997573719 cites W2047442562 @default.
• W1997573719 cites W2054514807 @default.
• W1997573719 cites W2063399248 @default.
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• W1997573719 cites W2067525676 @default.
• W1997573719 cites W2072588104 @default.
• W1997573719 cites W2075578030 @default.
• W1997573719 cites W2075629151 @default.
• W1997573719 cites W2080671562 @default.
• W1997573719 cites W2080786846 @default.
• W1997573719 cites W2083101816 @default.
• W1997573719 cites W2086997985 @default.
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• W1997573719 cites W2160929481 @default.
• W1997573719 cites W2168314498 @default.
• W1997573719 cites W2170787564 @default.
• W1997573719 cites W2231112245 @default.
• W1997573719 cites W23835451 @default.
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• W1997573719 doi "https://doi.org/10.4331/wjbc.v2.i10.215" @default.
• W1997573719 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3202125" @default.
• W1997573719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22031844" @default.
• W1997573719 hasPublicationYear "2011" @default.
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