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- W1997575345 abstract "The small adrenal cortex of SGA infants may play a role in the pathogenesis of their frequent postnatal problems. We therefore evaluated adrenocortical function of SGA infants at birth and during postnatal adaptation. In 22 vaginally delivered term infants (SGA <3rd. perc.,n=10; AGA,n=12) plasma aldosterone (Aldo), corticosterone(B),11-deoxycorticosterone (DOC), progesterone (P), 17-hydroxyprogesterone (17OHP), 11-deoxycortisol (S), cortisol (F) and cortisone (E) were longitudinally measured by multisteroid analysis by specific RIAs after Sephadex LH-20 chromatography in 250 μl samples # Relevant results are given in the table (mean values in ng/ml; * SGA vs AGA p < 0.05). Conclusions: Obviously, SGA infants are maintaining high Aldo levels throughout the first week of life which points to an increased activity of the Renin-Angiotensin-Aldo-Axis. In contrast, the low levels of active (B,F) and inactive (S,E) glucocorticoids at 2 h and 12 h may reflect a reduced response to the stress of birth in SGA infants. # Blood samples taken of routine blood sampling." @default.
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- W1997575345 date "1985-10-01" @default.
- W1997575345 modified "2023-09-25" @default.
- W1997575345 title "SMALL FOR GESTATIONAL AGE (SGA) INFANTS: PLASMA MINERALOCORTICOIDS, GLUCOCORTICOIDS AND PR0GESTINS AT BIRTH AND DURING THE NEONATAL PERIOD" @default.
- W1997575345 doi "https://doi.org/10.1203/00006450-198510000-00070" @default.
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