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• W1997581462 abstract "The store-mediated Ca 2+ entry was detected in single and cluster of rat submandibular acinar cells by measuring the Ca 2+ activated ionic membrane currents. In the cells where intracellular Ca 2+ was partly depleted by stimulation with submaximal concentration of acetylcholine (ACh) under a Ca 2+ -free extracellular condition, an employment of external Ca 2+ in the absence of ACh caused a sustained increase of the K + current without affecting the Cl − current. A renewed ACh challenge without external Ca 2+ caused repetitive spikes of both K + and Cl − currents due to the Ca 2+ release. SK & F 96365 inhibited the generation of the sustained K + current and refilling of the Ca 2+ store following the Ca 2+ readmission. It is suggested that the Ca 2+ enters the cell through the store-mediated pathway near the K + channels and is taken up by the store. Thus, only Ca 2+ released from the store can activate both the K + and Cl − currents." @default.
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• W1997581462 date "1995-11-01" @default.
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• W1997581462 title "Ca2+ entry through the store-mediated pathway directly activates only the K+ current but the subsequent Ca2+ release from the store activates both K+ and Cl− currents in submandibular gland acinar cells of the rat" @default.
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• W1997581462 doi "https://doi.org/10.1016/0898-6568(95)02006-3" @default.
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