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• W1997595910 abstract "Sleep disruption is a frequent occurrence in modern society. Whereas many studies have focused on the consequences of total sleep deprivation, few have investigated the condition of sleep disruption.We disrupted sleep of mice during the light period for 9 consecutive days using an intermittently rotating disc.Electroencephalogram (EEG) data demonstrated that non-rapid eye movement (NREM) sleep was severely fragmented and REM sleep was essentially abolished during the 12h light period. During the dark period, when sleep was not disrupted, neither NREM sleep nor REM sleep times differed from control values. Analysis of the EEG revealed a trend for increased power in the peak frequency of the NREM EEG spectra during the dark period. The fragmentation protocol was not overly stressful as body weights and water consumption remained unchanged, and plasma corticosterone did not differ between mice subjected to 3 or 9 days of sleep disruption and home cage controls. However, mice subjected to 9 days of sleep disruption by this method responded to lipopolysaccharide with an exacerbated febrile response.Existing methods to disrupt sleep of laboratory rodents often subject the animal to excessive locomotion, vibration, or sudden movements. This method does not suffer from any of these confounds.This study demonstrates that prolonged sleep disruption of mice exacerbates febrile responses to lipopolysaccharide. This device provides a method to determine mechanisms by which chronic insufficient sleep contributes to the etiology of many pathologies, particularly those with an inflammatory component." @default.
• W1997595910 created "2016-06-24" @default.
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• W1997595910 date "2013-09-01" @default.
• W1997595910 modified "2023-09-27" @default.
• W1997595910 title "Prolonged sleep fragmentation of mice exacerbates febrile responses to lipopolysaccharide" @default.
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• W1997595910 cites W1575558149 @default.
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• W1997595910 cites W1596295539 @default.
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• W1997595910 cites W1758200084 @default.
• W1997595910 cites W1818859001 @default.
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• W1997595910 cites W1972378352 @default.
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• W1997595910 cites W1990147895 @default.
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• W1997595910 doi "https://doi.org/10.1016/j.jneumeth.2013.07.008" @default.
• W1997595910 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3993011" @default.
• W1997595910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23872243" @default.
• W1997595910 hasPublicationYear "2013" @default.
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