FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997597645> ?p ?o ?g. }

• W1997597645 endingPage "82" @default.
• W1997597645 startingPage "71" @default.
• W1997597645 abstract "Human tissue contents of gliostatin/platelet-derived endothelial cell growth factor (PD-ECGF) and its drug-induced expression in tumor cells were currently examined by a sandwich enzyme immunoassay (EIA) system and a reverse transcription-polymerase chain reaction (RT-PCR) method. Gliostatin/PD-ECGF was found to distribute in rather ubiquitous than specific human tissues and organs, with a relatively high levels in the tissues of digestive system (esophagus and rectum), brain, spleen, bladder and lung, but not in gall bladder, aorta, muscle, fat and kidney. Most of examined human tumor cell lines showed 4- or 5-fold higher contents (21.5 ± 3.9 ng/mg protein) than normal tissue contents (4.4 ± 1.1 ng/mg protein) on the average. While gliostatin/PD-ECGF is known to lack a signal sequence, some tumor cells (A431 and MKN74) appeared to release it into the conditioned medium. Expression of gliostatin/PD-ECGF in epidermoid carcinoma cell (A431) and stomach cancer cell (MKN45) was induced by dibutyryl cyclic AMP and phorbol ester, and uniquely in MKN45 by hydrocortisone. In particular, this hydrocortisone specifically caused an increase of the apparent secretion of MKN74 without its cytotoxic effects, suggesting a possible secretion of gliostatin/PD-ECGF in the restricted but not universal cell line. Biological significance on the chemical induction of gliostatin/PD-ECGF in tumor cells and on its extracellular secretion are discussed." @default.
• W1997597645 created "2016-06-24" @default.
• W1997597645 creator A5017814619 @default.
• W1997597645 creator A5038157809 @default.
• W1997597645 creator A5079155623 @default.
• W1997597645 creator A5088517606 @default.
• W1997597645 creator A5008305666 @default.
• W1997597645 date "1996-11-01" @default.
• W1997597645 modified "2023-10-13" @default.
• W1997597645 title "Tissue distribution of human gliostatin/platelet-derived endothelial cell growth factor (PD-ECGF) and its drug-induced expression" @default.
• W1997597645 cites W121387658 @default.
• W1997597645 cites W1500574152 @default.
• W1997597645 cites W1519604321 @default.
• W1997597645 cites W1530960899 @default.
• W1997597645 cites W1537854451 @default.
• W1997597645 cites W1881900550 @default.
• W1997597645 cites W1972837174 @default.
• W1997597645 cites W1975081101 @default.
• W1997597645 cites W1978347107 @default.
• W1997597645 cites W1983478693 @default.
• W1997597645 cites W1984648137 @default.
• W1997597645 cites W1989839576 @default.
• W1997597645 cites W2007169317 @default.
• W1997597645 cites W2019354053 @default.
• W1997597645 cites W2020268778 @default.
• W1997597645 cites W2033158086 @default.
• W1997597645 cites W2036649302 @default.
• W1997597645 cites W2036895735 @default.
• W1997597645 cites W2043213673 @default.
• W1997597645 cites W2059287983 @default.
• W1997597645 cites W2095181507 @default.
• W1997597645 cites W2106363877 @default.
• W1997597645 cites W2129886990 @default.
• W1997597645 cites W2151598389 @default.
• W1997597645 cites W2158658626 @default.
• W1997597645 cites W4294216491 @default.
• W1997597645 doi "https://doi.org/10.1016/s0167-4889(96)00078-x" @default.
• W1997597645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8972720" @default.
• W1997597645 hasPublicationYear "1996" @default.
• W1997597645 type Work @default.
• W1997597645 sameAs 1997597645 @default.
• W1997597645 citedByCount "34" @default.
• W1997597645 countsByYear W19975976452012 @default.
• W1997597645 countsByYear W19975976452013 @default.
• W1997597645 countsByYear W19975976452015 @default.
• W1997597645 countsByYear W19975976452019 @default.
• W1997597645 countsByYear W19975976452021 @default.
• W1997597645 countsByYear W19975976452022 @default.
• W1997597645 crossrefType "journal-article" @default.
• W1997597645 hasAuthorship W1997597645A5008305666 @default.
• W1997597645 hasAuthorship W1997597645A5017814619 @default.
• W1997597645 hasAuthorship W1997597645A5038157809 @default.
• W1997597645 hasAuthorship W1997597645A5079155623 @default.
• W1997597645 hasAuthorship W1997597645A5088517606 @default.
• W1997597645 hasBestOaLocation W19975976451 @default.
• W1997597645 hasConcept C126322002 @default.
• W1997597645 hasConcept C134018914 @default.
• W1997597645 hasConcept C1491633281 @default.
• W1997597645 hasConcept C153911025 @default.
• W1997597645 hasConcept C154317977 @default.
• W1997597645 hasConcept C202751555 @default.
• W1997597645 hasConcept C2777546739 @default.
• W1997597645 hasConcept C2781018059 @default.
• W1997597645 hasConcept C29537977 @default.
• W1997597645 hasConcept C2994460389 @default.
• W1997597645 hasConcept C47170353 @default.
• W1997597645 hasConcept C49039625 @default.
• W1997597645 hasConcept C54355233 @default.
• W1997597645 hasConcept C55493867 @default.
• W1997597645 hasConcept C71924100 @default.
• W1997597645 hasConcept C81885089 @default.
• W1997597645 hasConcept C86803240 @default.
• W1997597645 hasConceptScore W1997597645C126322002 @default.
• W1997597645 hasConceptScore W1997597645C134018914 @default.
• W1997597645 hasConceptScore W1997597645C1491633281 @default.
• W1997597645 hasConceptScore W1997597645C153911025 @default.
• W1997597645 hasConceptScore W1997597645C154317977 @default.
• W1997597645 hasConceptScore W1997597645C202751555 @default.
• W1997597645 hasConceptScore W1997597645C2777546739 @default.
• W1997597645 hasConceptScore W1997597645C2781018059 @default.
• W1997597645 hasConceptScore W1997597645C29537977 @default.
• W1997597645 hasConceptScore W1997597645C2994460389 @default.
• W1997597645 hasConceptScore W1997597645C47170353 @default.
• W1997597645 hasConceptScore W1997597645C49039625 @default.
• W1997597645 hasConceptScore W1997597645C54355233 @default.
• W1997597645 hasConceptScore W1997597645C55493867 @default.
• W1997597645 hasConceptScore W1997597645C71924100 @default.
• W1997597645 hasConceptScore W1997597645C81885089 @default.
• W1997597645 hasConceptScore W1997597645C86803240 @default.
• W1997597645 hasIssue "1-2" @default.
• W1997597645 hasLocation W19975976451 @default.
• W1997597645 hasLocation W19975976452 @default.
• W1997597645 hasOpenAccess W1997597645 @default.
• W1997597645 hasPrimaryLocation W19975976451 @default.
• W1997597645 hasRelatedWork W130655387 @default.
• W1997597645 hasRelatedWork W1610468465 @default.
• W1997597645 hasRelatedWork W1995813336 @default.
• W1997597645 hasRelatedWork W1997819612 @default.

• next