Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997606952> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W1997606952 endingPage "227" @default.
- W1997606952 startingPage "224" @default.
- W1997606952 abstract "Eristostatin, a low molecular weight polypeptide (MW 5725), was encapsulated within two biodegradable poly(lactic acid—glycolic acid) microspheres. In vitro release profiles from the microspheres exhibited fast initial release for up to several days, followed by very slow or no release. The later stage of the slow release was due to protein aggregation within the microspheres. A simple, noninvasive method to detect the protein aggregation within the microspheres has been developed: extraction of radiolabeled protein from the microspheres by a DC electric field into a polyacrylamide gel and subsequent exposure to a γ-ray sensitive film. Direct application of the degrading microspheres onto the sample loading zone of sodium dodecyl sulfate—polyacrylamide gel electrophoresis (SDS—PAGE) could successfully extract the monomelic and oligomeric proteins into the autoradiogram of a gel slab, while unextractable protein aggregates within the microspheres could be directly visualized in their loading position." @default.
- W1997606952 created "2016-06-24" @default.
- W1997606952 creator A5033927749 @default.
- W1997606952 creator A5045888331 @default.
- W1997606952 date "1995-03-01" @default.
- W1997606952 modified "2023-09-23" @default.
- W1997606952 title "In Vitro Release Profiles of Eristostatin from Biodegradable Polymeric Microspheres: Protein Aggregation Problem" @default.
- W1997606952 doi "https://doi.org/10.1021/bp00032a016" @default.
- W1997606952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7766104" @default.
- W1997606952 hasPublicationYear "1995" @default.
- W1997606952 type Work @default.
- W1997606952 sameAs 1997606952 @default.
- W1997606952 citedByCount "35" @default.
- W1997606952 countsByYear W19976069522012 @default.
- W1997606952 countsByYear W19976069522013 @default.
- W1997606952 countsByYear W19976069522014 @default.
- W1997606952 countsByYear W19976069522018 @default.
- W1997606952 crossrefType "journal-article" @default.
- W1997606952 hasAuthorship W1997606952A5033927749 @default.
- W1997606952 hasAuthorship W1997606952A5045888331 @default.
- W1997606952 hasConcept C101660505 @default.
- W1997606952 hasConcept C116084860 @default.
- W1997606952 hasConcept C127413603 @default.
- W1997606952 hasConcept C181199279 @default.
- W1997606952 hasConcept C185592680 @default.
- W1997606952 hasConcept C188027245 @default.
- W1997606952 hasConcept C189942447 @default.
- W1997606952 hasConcept C202751555 @default.
- W1997606952 hasConcept C2775920511 @default.
- W1997606952 hasConcept C2778862431 @default.
- W1997606952 hasConcept C2778913249 @default.
- W1997606952 hasConcept C2780472526 @default.
- W1997606952 hasConcept C40250595 @default.
- W1997606952 hasConcept C42360764 @default.
- W1997606952 hasConcept C43617362 @default.
- W1997606952 hasConcept C523546767 @default.
- W1997606952 hasConcept C54355233 @default.
- W1997606952 hasConcept C55493867 @default.
- W1997606952 hasConcept C86803240 @default.
- W1997606952 hasConceptScore W1997606952C101660505 @default.
- W1997606952 hasConceptScore W1997606952C116084860 @default.
- W1997606952 hasConceptScore W1997606952C127413603 @default.
- W1997606952 hasConceptScore W1997606952C181199279 @default.
- W1997606952 hasConceptScore W1997606952C185592680 @default.
- W1997606952 hasConceptScore W1997606952C188027245 @default.
- W1997606952 hasConceptScore W1997606952C189942447 @default.
- W1997606952 hasConceptScore W1997606952C202751555 @default.
- W1997606952 hasConceptScore W1997606952C2775920511 @default.
- W1997606952 hasConceptScore W1997606952C2778862431 @default.
- W1997606952 hasConceptScore W1997606952C2778913249 @default.
- W1997606952 hasConceptScore W1997606952C2780472526 @default.
- W1997606952 hasConceptScore W1997606952C40250595 @default.
- W1997606952 hasConceptScore W1997606952C42360764 @default.
- W1997606952 hasConceptScore W1997606952C43617362 @default.
- W1997606952 hasConceptScore W1997606952C523546767 @default.
- W1997606952 hasConceptScore W1997606952C54355233 @default.
- W1997606952 hasConceptScore W1997606952C55493867 @default.
- W1997606952 hasConceptScore W1997606952C86803240 @default.
- W1997606952 hasIssue "2" @default.
- W1997606952 hasLocation W19976069521 @default.
- W1997606952 hasLocation W19976069522 @default.
- W1997606952 hasOpenAccess W1997606952 @default.
- W1997606952 hasPrimaryLocation W19976069521 @default.
- W1997606952 hasRelatedWork W1607780302 @default.
- W1997606952 hasRelatedWork W1625221918 @default.
- W1997606952 hasRelatedWork W1971924662 @default.
- W1997606952 hasRelatedWork W1997606952 @default.
- W1997606952 hasRelatedWork W2006391431 @default.
- W1997606952 hasRelatedWork W2009885565 @default.
- W1997606952 hasRelatedWork W2018781929 @default.
- W1997606952 hasRelatedWork W2049881746 @default.
- W1997606952 hasRelatedWork W2061960997 @default.
- W1997606952 hasRelatedWork W993277546 @default.
- W1997606952 hasVolume "11" @default.
- W1997606952 isParatext "false" @default.
- W1997606952 isRetracted "false" @default.
- W1997606952 magId "1997606952" @default.
- W1997606952 workType "article" @default.