Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997636692> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1997636692 endingPage "2882" @default.
- W1997636692 startingPage "2877" @default.
- W1997636692 abstract "Specific binding sites for PRL were identified on isolated intestinal epithelial cells from both male and female rabbits. These receptors exhibited a very high affinity for PRL (Kd = 5 x 10(-11) M) and were immunologically very similar to the well characterized mammary PRL receptor. About 3500 PRL receptors/cell were expressed on isolated epithelial cells from rabbit jejunum. These receptors were distributed in precise portions of the gut, being highly expressed in the proximal small intestine (duodenum and jejunum), moderately expressed in the ileum, and barely detectable in the colon. The levels of intestinal epithelial PRL receptors were low in 15-day-old rabbits, moderate at 1 month, and reached adult levels at 2 months, indicating enhanced PRL receptor expression in the intestine as development proceeded. The PRL receptor gene was specifically and highly expressed in the rabbit intestine, and four PRL receptor transcripts were detected that were identical to the transcripts characterized in the mammary gland. In individual intestinal segments, the expression of PRL-binding sites was always highly correlated with the level of PRL receptor mRNA. These results show that isolated intestinal epithelial cells express the PRL receptor gene as well as specific binding sites with a high affinity for PRL. They suggest that PRL regulates intestinal functions by exerting direct actions on the intestinal epithelial cells." @default.
- W1997636692 created "2016-06-24" @default.
- W1997636692 creator A5009987807 @default.
- W1997636692 creator A5028471780 @default.
- W1997636692 creator A5052850973 @default.
- W1997636692 creator A5087892875 @default.
- W1997636692 date "1992-05-01" @default.
- W1997636692 modified "2023-10-18" @default.
- W1997636692 title "Expression of prolactin (PRL) receptor gene and PRL-binding sites in rabbit intestinal epithelial cells." @default.
- W1997636692 cites W1472088445 @default.
- W1997636692 cites W1533065494 @default.
- W1997636692 cites W1533442065 @default.
- W1997636692 cites W1964961772 @default.
- W1997636692 cites W1975179558 @default.
- W1997636692 cites W1983994437 @default.
- W1997636692 cites W2008184265 @default.
- W1997636692 cites W2015738333 @default.
- W1997636692 cites W2026322847 @default.
- W1997636692 cites W2039383540 @default.
- W1997636692 cites W2044749916 @default.
- W1997636692 cites W2048231430 @default.
- W1997636692 cites W2050989895 @default.
- W1997636692 cites W2060275965 @default.
- W1997636692 cites W2062822987 @default.
- W1997636692 cites W2072821203 @default.
- W1997636692 cites W2080834531 @default.
- W1997636692 cites W2086341665 @default.
- W1997636692 cites W2134812217 @default.
- W1997636692 cites W2142178316 @default.
- W1997636692 cites W2399845308 @default.
- W1997636692 cites W2413554891 @default.
- W1997636692 cites W2601837005 @default.
- W1997636692 cites W1980909969 @default.
- W1997636692 doi "https://doi.org/10.1210/endo.130.5.1572300" @default.
- W1997636692 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1572300" @default.
- W1997636692 hasPublicationYear "1992" @default.
- W1997636692 type Work @default.
- W1997636692 sameAs 1997636692 @default.
- W1997636692 citedByCount "14" @default.
- W1997636692 countsByYear W19976366922014 @default.
- W1997636692 countsByYear W19976366922020 @default.
- W1997636692 crossrefType "journal-article" @default.
- W1997636692 hasAuthorship W1997636692A5009987807 @default.
- W1997636692 hasAuthorship W1997636692A5028471780 @default.
- W1997636692 hasAuthorship W1997636692A5052850973 @default.
- W1997636692 hasAuthorship W1997636692A5087892875 @default.
- W1997636692 hasConcept C126322002 @default.
- W1997636692 hasConcept C134018914 @default.
- W1997636692 hasConcept C170493617 @default.
- W1997636692 hasConcept C2776366702 @default.
- W1997636692 hasConcept C2777226302 @default.
- W1997636692 hasConcept C2777882243 @default.
- W1997636692 hasConcept C2779064019 @default.
- W1997636692 hasConcept C2781031661 @default.
- W1997636692 hasConcept C529295009 @default.
- W1997636692 hasConcept C54355233 @default.
- W1997636692 hasConcept C55493867 @default.
- W1997636692 hasConcept C71315377 @default.
- W1997636692 hasConcept C71924100 @default.
- W1997636692 hasConcept C86803240 @default.
- W1997636692 hasConceptScore W1997636692C126322002 @default.
- W1997636692 hasConceptScore W1997636692C134018914 @default.
- W1997636692 hasConceptScore W1997636692C170493617 @default.
- W1997636692 hasConceptScore W1997636692C2776366702 @default.
- W1997636692 hasConceptScore W1997636692C2777226302 @default.
- W1997636692 hasConceptScore W1997636692C2777882243 @default.
- W1997636692 hasConceptScore W1997636692C2779064019 @default.
- W1997636692 hasConceptScore W1997636692C2781031661 @default.
- W1997636692 hasConceptScore W1997636692C529295009 @default.
- W1997636692 hasConceptScore W1997636692C54355233 @default.
- W1997636692 hasConceptScore W1997636692C55493867 @default.
- W1997636692 hasConceptScore W1997636692C71315377 @default.
- W1997636692 hasConceptScore W1997636692C71924100 @default.
- W1997636692 hasConceptScore W1997636692C86803240 @default.
- W1997636692 hasIssue "5" @default.
- W1997636692 hasLocation W19976366921 @default.
- W1997636692 hasLocation W19976366922 @default.
- W1997636692 hasOpenAccess W1997636692 @default.
- W1997636692 hasPrimaryLocation W19976366921 @default.
- W1997636692 hasRelatedWork W1963919935 @default.
- W1997636692 hasRelatedWork W1983571825 @default.
- W1997636692 hasRelatedWork W1990399071 @default.
- W1997636692 hasRelatedWork W2034833546 @default.
- W1997636692 hasRelatedWork W2035021492 @default.
- W1997636692 hasRelatedWork W2083893199 @default.
- W1997636692 hasRelatedWork W2114525053 @default.
- W1997636692 hasRelatedWork W2156572066 @default.
- W1997636692 hasRelatedWork W2312785282 @default.
- W1997636692 hasRelatedWork W2418697285 @default.
- W1997636692 hasVolume "130" @default.
- W1997636692 isParatext "false" @default.
- W1997636692 isRetracted "false" @default.
- W1997636692 magId "1997636692" @default.
- W1997636692 workType "article" @default.