FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997673361> ?p ?o ?g. }

• W1997673361 endingPage "2459" @default.
• W1997673361 startingPage "2446" @default.
• W1997673361 abstract "Andes virus (ANDV) is the predominant etiologic agent of hantavirus cardiopulmonary syndrome (HCPS) in southern South America. In Chile, serologically confirmed human hantavirus infections have occurred throughout a wide latitudinal distribution extending from the regions of Valparaíso (32 to 33 degrees S) to Aysén (46 degrees S) in southern Patagonia. In this study, we found seropositive rodents further north in the Coquimbo region (30 degrees S) in Chile. Rodent seroprevalence was 1.4%, with Oligoryzomys longicaudatus displaying the highest seroprevalence (5.9%), followed by Abrothrix longipilis (1.9%) and other species exhibiting </=0.6% seropositivity. We sequenced partial ANDV small (S) segment RNA from 6 HCPS patients and 32 rodents of four different species collected throughout the known range of hantavirus infection in Chile. Phylogenetic analyses showed two major ANDV South (ANDV Sout) clades, congruent with two major Chilean ecoregions, Mediterranean (Chilean matorral [shrubland]) and Valdivian temperate forest. Human and rodent samples grouped according to geographic location. Phylogenetic comparative analyses of portions of S and medium segments (encoding glycoproteins Gn and Gc) from a subset of rodent specimens exhibited similar topologies, corroborating two major ANDV Sout clades in Chile and suggesting that yet unknown factors influence viral gene flow and persistence throughout the two Chilean ecoregions. Genetic algorithms for recombination detection identified recombination events within the S segment. Molecular demographic analyses showed that the virus is undergoing purifying selection and demonstrated a recent exponential growth in the effective number of ANDV Sout infections in Chile that correlates with the increased number of human cases reported. Although we determined virus sequences from four rodent species, our results confirmed O. longicaudatus as the primary ANDV Sout reservoir in Chile. While evidence of geographic differentiation exists, a single cosmopolitan lineage of ANDV Sout remains the sole etiologic agent for HCPS in Chile." @default.
• W1997673361 created "2016-06-24" @default.
• W1997673361 creator A5006921747 @default.
• W1997673361 creator A5011131525 @default.
• W1997673361 creator A5018466470 @default.
• W1997673361 creator A5056313483 @default.
• W1997673361 creator A5080092788 @default.
• W1997673361 creator A5082430364 @default.
• W1997673361 creator A5089650762 @default.
• W1997673361 creator A5091662374 @default.
• W1997673361 creator A5091717380 @default.
• W1997673361 date "2009-03-15" @default.
• W1997673361 modified "2023-10-14" @default.
• W1997673361 title "Ecology, Genetic Diversity, and Phylogeographic Structure of Andes Virus in Humans and Rodents in Chile" @default.
• W1997673361 cites W1915699870 @default.
• W1997673361 cites W1970694974 @default.
• W1997673361 cites W1972015592 @default.
• W1997673361 cites W1972944084 @default.
• W1997673361 cites W1973194618 @default.
• W1997673361 cites W1981152907 @default.
• W1997673361 cites W2030966943 @default.
• W1997673361 cites W2042806515 @default.
• W1997673361 cites W2045681061 @default.
• W1997673361 cites W2051363072 @default.
• W1997673361 cites W2064650699 @default.
• W1997673361 cites W2064803653 @default.
• W1997673361 cites W2065033137 @default.
• W1997673361 cites W2082928585 @default.
• W1997673361 cites W2095292349 @default.
• W1997673361 cites W2096420865 @default.
• W1997673361 cites W2100423485 @default.
• W1997673361 cites W2100444509 @default.
• W1997673361 cites W2101546326 @default.
• W1997673361 cites W2102234847 @default.
• W1997673361 cites W2107097514 @default.
• W1997673361 cites W2108132790 @default.
• W1997673361 cites W2110252506 @default.
• W1997673361 cites W2110835349 @default.
• W1997673361 cites W2111300387 @default.
• W1997673361 cites W2112278655 @default.
• W1997673361 cites W2112399515 @default.
• W1997673361 cites W2115837217 @default.
• W1997673361 cites W2119034584 @default.
• W1997673361 cites W2119192181 @default.
• W1997673361 cites W2120904614 @default.
• W1997673361 cites W2121909584 @default.
• W1997673361 cites W2127170357 @default.
• W1997673361 cites W2129690464 @default.
• W1997673361 cites W2131203559 @default.
• W1997673361 cites W2134239284 @default.
• W1997673361 cites W2135763337 @default.
• W1997673361 cites W2136847298 @default.
• W1997673361 cites W2138178197 @default.
• W1997673361 cites W2139440925 @default.
• W1997673361 cites W2142152875 @default.
• W1997673361 cites W2144654387 @default.
• W1997673361 cites W2147710356 @default.
• W1997673361 cites W2147822528 @default.
• W1997673361 cites W2148510698 @default.
• W1997673361 cites W2153432740 @default.
• W1997673361 cites W2157164556 @default.
• W1997673361 cites W2161444534 @default.
• W1997673361 cites W2161808504 @default.
• W1997673361 cites W2162421185 @default.
• W1997673361 cites W2170631436 @default.
• W1997673361 cites W2170996473 @default.
• W1997673361 cites W2173956664 @default.
• W1997673361 cites W2272473773 @default.
• W1997673361 cites W38658713 @default.
• W1997673361 doi "https://doi.org/10.1128/jvi.01057-08" @default.
• W1997673361 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2648280" @default.
• W1997673361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19116256" @default.
• W1997673361 hasPublicationYear "2009" @default.
• W1997673361 type Work @default.
• W1997673361 sameAs 1997673361 @default.
• W1997673361 citedByCount "61" @default.
• W1997673361 countsByYear W19976733612012 @default.
• W1997673361 countsByYear W19976733612013 @default.
• W1997673361 countsByYear W19976733612014 @default.
• W1997673361 countsByYear W19976733612015 @default.
• W1997673361 countsByYear W19976733612016 @default.
• W1997673361 countsByYear W19976733612017 @default.
• W1997673361 countsByYear W19976733612018 @default.
• W1997673361 countsByYear W19976733612019 @default.
• W1997673361 countsByYear W19976733612020 @default.
• W1997673361 countsByYear W19976733612021 @default.
• W1997673361 countsByYear W19976733612023 @default.
• W1997673361 crossrefType "journal-article" @default.
• W1997673361 hasAuthorship W1997673361A5006921747 @default.
• W1997673361 hasAuthorship W1997673361A5011131525 @default.
• W1997673361 hasAuthorship W1997673361A5018466470 @default.
• W1997673361 hasAuthorship W1997673361A5056313483 @default.
• W1997673361 hasAuthorship W1997673361A5080092788 @default.
• W1997673361 hasAuthorship W1997673361A5082430364 @default.
• W1997673361 hasAuthorship W1997673361A5089650762 @default.
• W1997673361 hasAuthorship W1997673361A5091662374 @default.
• W1997673361 hasAuthorship W1997673361A5091717380 @default.
• W1997673361 hasBestOaLocation W19976733611 @default.

• next