FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997688652> ?p ?o ?g. }

• W1997688652 endingPage "914" @default.
• W1997688652 startingPage "910" @default.
• W1997688652 abstract "Objective. The availability of new-generation drugs has provided significant success reflected by disease activity markers and clinical status in AS, but controversial reports necessitate further assessment of associated increased risk of cardiovascular burden that might persist. Hence this prospective clinical study evaluated the effectiveness of a 24-week anti-TNF-α therapy on vascular stiffness [pulse wave velocity (PWV)] in AS. Methods. A total of 28 active AS patients (21 males, 7 females) were enrolled before the start of biologic therapy. Demographic and clinical characteristics were recorded. Arterial stiffness was assessed using PWV. Patients were evaluated before and 24 weeks after anti-TNF-α therapy. Results. The mean disease duration was 8.4 (4.9) years. After 24 weeks of anti-TNF-α therapy, despite significant improvements in patients’ symptoms and clinical activity parameters, including BASDAI score [4.9 (0.9) vs 1.9 (0.5), P = 0.0001], ESR [35.5 (23.1) vs 13.8 (9.2) mm/h, P = 0.0001) and CRP level [2.1 (1.6) vs 0.4 (0.3) ng/dl, P = 0.0001], no significant change was seen in arterial stiffness parameters [7.9 (1.3) vs 7.7 (1.3) m/s, P = 0.412]. Significant correlation was determined between arterial stiffness and age, systolic blood pressure and high-density lipoprotein cholesterol levels. Conclusion. Despite significant improvement in markers of disease activity, anti-TNF-α therapy does not seem to improve arterial stiffness, a significant AS-associated cardiovascular burden. Thus, when treating AS, significant end-points other than DASs should also be considered, and any hidden threat like arterial stiffness should be addressed further." @default.
• W1997688652 created "2016-06-24" @default.
• W1997688652 creator A5004909872 @default.
• W1997688652 creator A5016665857 @default.
• W1997688652 creator A5017106566 @default.
• W1997688652 creator A5027518761 @default.
• W1997688652 creator A5035817129 @default.
• W1997688652 creator A5040345884 @default.
• W1997688652 creator A5044320853 @default.
• W1997688652 creator A5044528928 @default.
• W1997688652 date "2012-01-16" @default.
• W1997688652 modified "2023-09-25" @default.
• W1997688652 title "Anti-TNF- therapy may not improve arterial stiffness in patients with AS: a 24-week follow-up" @default.
• W1997688652 cites W122349615 @default.
• W1997688652 cites W1515255326 @default.
• W1997688652 cites W1870121838 @default.
• W1997688652 cites W1966756689 @default.
• W1997688652 cites W1975748073 @default.
• W1997688652 cites W1988195204 @default.
• W1997688652 cites W1999190495 @default.
• W1997688652 cites W1999247995 @default.
• W1997688652 cites W1999679918 @default.
• W1997688652 cites W2001056724 @default.
• W1997688652 cites W2007732956 @default.
• W1997688652 cites W2033017593 @default.
• W1997688652 cites W2038759195 @default.
• W1997688652 cites W2045378100 @default.
• W1997688652 cites W2054260410 @default.
• W1997688652 cites W2068219050 @default.
• W1997688652 cites W2070073147 @default.
• W1997688652 cites W2072142124 @default.
• W1997688652 cites W2073477281 @default.
• W1997688652 cites W2075936775 @default.
• W1997688652 cites W2097730524 @default.
• W1997688652 cites W2099341021 @default.
• W1997688652 cites W2102935782 @default.
• W1997688652 cites W2113325877 @default.
• W1997688652 cites W2114231652 @default.
• W1997688652 cites W2121119076 @default.
• W1997688652 cites W2123806340 @default.
• W1997688652 cites W2128534628 @default.
• W1997688652 cites W2138209376 @default.
• W1997688652 cites W2144494434 @default.
• W1997688652 cites W2155957615 @default.
• W1997688652 cites W2517090051 @default.
• W1997688652 doi "https://doi.org/10.1093/rheumatology/ker434" @default.
• W1997688652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22253025" @default.
• W1997688652 hasPublicationYear "2012" @default.
• W1997688652 type Work @default.
• W1997688652 sameAs 1997688652 @default.
• W1997688652 citedByCount "39" @default.
• W1997688652 countsByYear W19976886522012 @default.
• W1997688652 countsByYear W19976886522013 @default.
• W1997688652 countsByYear W19976886522014 @default.
• W1997688652 countsByYear W19976886522015 @default.
• W1997688652 countsByYear W19976886522016 @default.
• W1997688652 countsByYear W19976886522017 @default.
• W1997688652 countsByYear W19976886522018 @default.
• W1997688652 countsByYear W19976886522019 @default.
• W1997688652 countsByYear W19976886522020 @default.
• W1997688652 countsByYear W19976886522021 @default.
• W1997688652 countsByYear W19976886522022 @default.
• W1997688652 countsByYear W19976886522023 @default.
• W1997688652 crossrefType "journal-article" @default.
• W1997688652 hasAuthorship W1997688652A5004909872 @default.
• W1997688652 hasAuthorship W1997688652A5016665857 @default.
• W1997688652 hasAuthorship W1997688652A5017106566 @default.
• W1997688652 hasAuthorship W1997688652A5027518761 @default.
• W1997688652 hasAuthorship W1997688652A5035817129 @default.
• W1997688652 hasAuthorship W1997688652A5040345884 @default.
• W1997688652 hasAuthorship W1997688652A5044320853 @default.
• W1997688652 hasAuthorship W1997688652A5044528928 @default.
• W1997688652 hasConcept C126322002 @default.
• W1997688652 hasConcept C141071460 @default.
• W1997688652 hasConcept C164705383 @default.
• W1997688652 hasConcept C188816634 @default.
• W1997688652 hasConcept C2775850156 @default.
• W1997688652 hasConcept C2778319312 @default.
• W1997688652 hasConcept C71924100 @default.
• W1997688652 hasConcept C84393581 @default.
• W1997688652 hasConcept C90924648 @default.
• W1997688652 hasConceptScore W1997688652C126322002 @default.
• W1997688652 hasConceptScore W1997688652C141071460 @default.
• W1997688652 hasConceptScore W1997688652C164705383 @default.
• W1997688652 hasConceptScore W1997688652C188816634 @default.
• W1997688652 hasConceptScore W1997688652C2775850156 @default.
• W1997688652 hasConceptScore W1997688652C2778319312 @default.
• W1997688652 hasConceptScore W1997688652C71924100 @default.
• W1997688652 hasConceptScore W1997688652C84393581 @default.
• W1997688652 hasConceptScore W1997688652C90924648 @default.
• W1997688652 hasIssue "5" @default.
• W1997688652 hasLocation W19976886521 @default.
• W1997688652 hasLocation W19976886522 @default.
• W1997688652 hasOpenAccess W1997688652 @default.
• W1997688652 hasPrimaryLocation W19976886521 @default.
• W1997688652 hasRelatedWork W2078297210 @default.
• W1997688652 hasRelatedWork W2097766117 @default.
• W1997688652 hasRelatedWork W2119148367 @default.

• next