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- W1997712586 abstract "The conductance of the toad (Bufo bufo) lens membranes is 4·6 × 10−4 mho cm−2. This compares with 5·0 × 10−4 mho cm−2 for the equilibrium conductance calculated from potassium and chloride flux data. Values of 5·2 and 5·1 × 10−4 mho cm−2 are obtained by substituting sodium, potassium and chloride concentration and permeability data into the Goldman and Kimizuka-Koketsu conductance equations. As the computed values are greater than the measured conductance, exchange diffusion of ions, particularly of chloride, probably takes place across the lens membranes. Computed values corrected for exchange diffusion are 4·4 and 4·3 × 10−4 mho cm−2, respectively. Substituting potassium for sodium in the solution bathing the lens results in an increase in conductance, while replacing sodium by choline or chloride by benzene-sulphonate both result in a decrease in conductance. The changes in conductance are best predicted by the Kimizuka-Koketsu equations. In acid DNP solutions, DNP enters the lens rapidly. There is a rapid depolarization of the lens membrane potential and a marked increase in membrane conductance. The effects on the membrane can be accounted for if it is assumed that the lens membranes are relatively permeable to the dinitrophenate ion. Again the conductance is best predicted by the Kimizuka-Koketsu model." @default.
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- W1997712586 date "1970-10-01" @default.
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- W1997712586 title "Effect of changes in external ion concentrations and 2,4-dinitrophenol on the conductance of toad lens membranes" @default.
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- W1997712586 doi "https://doi.org/10.1016/s0014-4835(70)80027-6" @default.
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