Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997720152> ?p ?o ?g. }
- W1997720152 endingPage "173" @default.
- W1997720152 startingPage "167" @default.
- W1997720152 abstract "Heart rate (HR), mean arterial pressure (MAP), indices of sympathetic and parasympathetic activity (plasma concentrations of adrenaline, noradrenaline and pancreatic polypeptide, PP), vasopressin (VP) and aldosterone (ALDO) were measured in six pigs during continuous bleeding resulting in hypovolaemic shock, from which five survived. Three stages of haemorrhage could be defined. Stage I. Resting MAP was 85 ± 6 mmHg and increased to 96 ± 5 mmHg with a blood loss of 275 (range 250–300) (10 (9–12)% of the estimated blood volume) concomitant with an increase in HR from 105 ± 5 to 113 ± 6 beats min-1 (P < 0.05). Stage II. After a blood loss of 375 (300–500) ml (15 (13–16)%) MAP fell to 62 ± 9 mmHg and HR to 95 ± 5 beats min-1 (P < 0.05). Stage III. A blood loss of 1113 (825–1450) ml (44 (30–52)%) resulted in a MAP of 50 ± 4 mmHg and an increase in HR to 206 ± 3 beats min-1 (P < 0.05). Adrenaline increased from 0.3 ± 0.1 to 0.8 ± 0.3 (stage II) and 3.6 ± 1.1 nmol l-1 (stage III) (P < 0.05); noradrenaline from 0.4 ± 0.1 to 1.5 ± 0.4 (stage II) and 5.9 ± 1.7 nmol l-1 (stage III) (P < 0.05); PP from 6.2 ± 1.6 to 13.3 ± 2.3 (stage II) and 20.9 ± 7.8 pmol l-1 (stage III) (P < 0.05). VP changed only marginally, but ALDO increased from 496 ± 54 to 623 ± 76 pmol l-1 (stage III) (P < 0.05). The results suggest that a high HR and intense sympathetic activity is seen during severe haemorrhage in the pig while vagal slowing of the heart and moderate hypotension are prominent when bleeding amounts to approximately 15% of the estimated blood volume." @default.
- W1997720152 created "2016-06-24" @default.
- W1997720152 creator A5005600302 @default.
- W1997720152 creator A5033154781 @default.
- W1997720152 creator A5050361725 @default.
- W1997720152 creator A5058889377 @default.
- W1997720152 creator A5077381140 @default.
- W1997720152 date "1990-02-01" @default.
- W1997720152 modified "2023-10-15" @default.
- W1997720152 title "Cardiovascular and endocrine responses to haemorrhage in the pig" @default.
- W1997720152 cites W1565165145 @default.
- W1997720152 cites W1977354154 @default.
- W1997720152 cites W1986165073 @default.
- W1997720152 cites W1989580194 @default.
- W1997720152 cites W1989955067 @default.
- W1997720152 cites W2023151805 @default.
- W1997720152 cites W2027370110 @default.
- W1997720152 cites W2036001104 @default.
- W1997720152 cites W2042897911 @default.
- W1997720152 cites W2064948682 @default.
- W1997720152 cites W2070052921 @default.
- W1997720152 cites W2072654952 @default.
- W1997720152 cites W2081859764 @default.
- W1997720152 cites W2084530950 @default.
- W1997720152 cites W2090783009 @default.
- W1997720152 cites W2102559260 @default.
- W1997720152 cites W2108436201 @default.
- W1997720152 cites W2123638888 @default.
- W1997720152 cites W2145297446 @default.
- W1997720152 cites W2153850654 @default.
- W1997720152 cites W2158209098 @default.
- W1997720152 cites W2178951657 @default.
- W1997720152 cites W2197849859 @default.
- W1997720152 cites W2298940726 @default.
- W1997720152 cites W2413896115 @default.
- W1997720152 cites W2912404188 @default.
- W1997720152 doi "https://doi.org/10.1111/j.1748-1716.1990.tb08829.x" @default.
- W1997720152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2316378" @default.
- W1997720152 hasPublicationYear "1990" @default.
- W1997720152 type Work @default.
- W1997720152 sameAs 1997720152 @default.
- W1997720152 citedByCount "42" @default.
- W1997720152 countsByYear W19977201522012 @default.
- W1997720152 countsByYear W19977201522013 @default.
- W1997720152 countsByYear W19977201522014 @default.
- W1997720152 countsByYear W19977201522015 @default.
- W1997720152 countsByYear W19977201522019 @default.
- W1997720152 countsByYear W19977201522021 @default.
- W1997720152 countsByYear W19977201522022 @default.
- W1997720152 crossrefType "journal-article" @default.
- W1997720152 hasAuthorship W1997720152A5005600302 @default.
- W1997720152 hasAuthorship W1997720152A5033154781 @default.
- W1997720152 hasAuthorship W1997720152A5050361725 @default.
- W1997720152 hasAuthorship W1997720152A5058889377 @default.
- W1997720152 hasAuthorship W1997720152A5077381140 @default.
- W1997720152 hasConcept C126322002 @default.
- W1997720152 hasConcept C134018914 @default.
- W1997720152 hasConcept C146357865 @default.
- W1997720152 hasConcept C151730666 @default.
- W1997720152 hasConcept C185592680 @default.
- W1997720152 hasConcept C2776370428 @default.
- W1997720152 hasConcept C2776452961 @default.
- W1997720152 hasConcept C2777953023 @default.
- W1997720152 hasConcept C2778525890 @default.
- W1997720152 hasConcept C71924100 @default.
- W1997720152 hasConcept C84393581 @default.
- W1997720152 hasConcept C86803240 @default.
- W1997720152 hasConceptScore W1997720152C126322002 @default.
- W1997720152 hasConceptScore W1997720152C134018914 @default.
- W1997720152 hasConceptScore W1997720152C146357865 @default.
- W1997720152 hasConceptScore W1997720152C151730666 @default.
- W1997720152 hasConceptScore W1997720152C185592680 @default.
- W1997720152 hasConceptScore W1997720152C2776370428 @default.
- W1997720152 hasConceptScore W1997720152C2776452961 @default.
- W1997720152 hasConceptScore W1997720152C2777953023 @default.
- W1997720152 hasConceptScore W1997720152C2778525890 @default.
- W1997720152 hasConceptScore W1997720152C71924100 @default.
- W1997720152 hasConceptScore W1997720152C84393581 @default.
- W1997720152 hasConceptScore W1997720152C86803240 @default.
- W1997720152 hasIssue "2" @default.
- W1997720152 hasLocation W19977201521 @default.
- W1997720152 hasLocation W19977201522 @default.
- W1997720152 hasOpenAccess W1997720152 @default.
- W1997720152 hasPrimaryLocation W19977201521 @default.
- W1997720152 hasRelatedWork W1982705383 @default.
- W1997720152 hasRelatedWork W2019747791 @default.
- W1997720152 hasRelatedWork W2044739765 @default.
- W1997720152 hasRelatedWork W2053436452 @default.
- W1997720152 hasRelatedWork W2096111588 @default.
- W1997720152 hasRelatedWork W2127847888 @default.
- W1997720152 hasRelatedWork W2270650034 @default.
- W1997720152 hasRelatedWork W2397391565 @default.
- W1997720152 hasRelatedWork W2888157337 @default.
- W1997720152 hasRelatedWork W4378675352 @default.
- W1997720152 hasVolume "138" @default.
- W1997720152 isParatext "false" @default.
- W1997720152 isRetracted "false" @default.
- W1997720152 magId "1997720152" @default.