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- W1997735043 abstract "Concentrations of the two predominant plasma proteinase inhibitors (α1-AT and α2-M), albumin, and total protein in newborn infants with hyaline membrane disease or other disorders were compared with those in normal preterm and full-term infants. During the first day, infants with hyaline membrane disease had significantly reduced levels of both inhibitors, both absolute and relative to total protein. α2-M levels were also low in infants with other forms of respiratory distress. On the second day, no significant differences were found. The relative lack of inhibition of proteinases and possibly of the vasoconstrictor effects of catecholamines and serotonin, whether primary or secondary, may play a role in the evolution of hyaline membrane disease. Concentrations of the two predominant plasma proteinase inhibitors (α1-AT and α2-M), albumin, and total protein in newborn infants with hyaline membrane disease or other disorders were compared with those in normal preterm and full-term infants. During the first day, infants with hyaline membrane disease had significantly reduced levels of both inhibitors, both absolute and relative to total protein. α2-M levels were also low in infants with other forms of respiratory distress. On the second day, no significant differences were found. The relative lack of inhibition of proteinases and possibly of the vasoconstrictor effects of catecholamines and serotonin, whether primary or secondary, may play a role in the evolution of hyaline membrane disease." @default.
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- W1997735043 date "1972-09-01" @default.
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- W1997735043 title "Serum proteinase inhibitors in infants with hyaline membrane disease" @default.
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- W1997735043 doi "https://doi.org/10.1016/s0022-3476(72)80196-3" @default.
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