Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997735375> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1997735375 endingPage "162" @default.
- W1997735375 startingPage "158" @default.
- W1997735375 abstract "Arterial oxygen saturation (S) is usually measured during inhalation challenges in infants as desaturation has been demonstrated with provoked bronchoconstriction. We wished to examine whether measurement of S would provide a simple noninvasive indicator of respiratory function (RF) changes occuring during inhalation challenge in infants. Histamine inhalation challenges were performed longitudinally in 22 normal healthy infants at 4 and 26 weeks of age. RF was measured by calculating maximum forced expiratory flow at functional residual capacity (VmaxFRC) using the rapid thoracic compression technique. Airway responsiveness was assessed using histamine; the provoking concentration (PC) was that which caused a fall in VmaxFRC of at least 40% from baseline. The provocative concentration for an exact fall of 40% in VmaxFRC (PC40) from baseline was derived by linear interpolation. S was continuously monitored by pulse oximetty. One month old infants had higher S levels throughout the inhalation challenge in comparison to their S levels at 6 months of age. Significant falls in S, were observed at the PC at both ages. However, at the age of 26 weeks the infants had greater median falls in S [PC, 4.5% (95%Cl: 3.0, 7.0)] compared to the response at age 4 weeks [3.0% (95%Cl: 1.0, 4.0) (P < 0.01)]. Median falls in VmaxFRC at the PC were not different between the ages. These results indicate an age-dependent discordance between airway and S response in healthy infants during histamine-induced bronchoconstriction. Pediatr Pulmonol. 1993; 16:158–162. © 1993 Wiley-Liss, Inc." @default.
- W1997735375 created "2016-06-24" @default.
- W1997735375 creator A5009385838 @default.
- W1997735375 creator A5037027314 @default.
- W1997735375 creator A5038285432 @default.
- W1997735375 creator A5040172919 @default.
- W1997735375 creator A5077636671 @default.
- W1997735375 date "1993-09-01" @default.
- W1997735375 modified "2023-10-14" @default.
- W1997735375 title "The effect of age on oxygen desaturation during histamine inhalation challenge in normal infants" @default.
- W1997735375 cites W2001105148 @default.
- W1997735375 cites W2002849934 @default.
- W1997735375 cites W2009615146 @default.
- W1997735375 cites W2027573541 @default.
- W1997735375 cites W2043015149 @default.
- W1997735375 cites W2070008624 @default.
- W1997735375 cites W2082089826 @default.
- W1997735375 cites W2134095727 @default.
- W1997735375 cites W2149733611 @default.
- W1997735375 cites W2153626824 @default.
- W1997735375 cites W2179330369 @default.
- W1997735375 cites W287198160 @default.
- W1997735375 doi "https://doi.org/10.1002/ppul.1950160304" @default.
- W1997735375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8309739" @default.
- W1997735375 hasPublicationYear "1993" @default.
- W1997735375 type Work @default.
- W1997735375 sameAs 1997735375 @default.
- W1997735375 citedByCount "11" @default.
- W1997735375 countsByYear W19977353752019 @default.
- W1997735375 crossrefType "journal-article" @default.
- W1997735375 hasAuthorship W1997735375A5009385838 @default.
- W1997735375 hasAuthorship W1997735375A5037027314 @default.
- W1997735375 hasAuthorship W1997735375A5038285432 @default.
- W1997735375 hasAuthorship W1997735375A5040172919 @default.
- W1997735375 hasAuthorship W1997735375A5077636671 @default.
- W1997735375 hasConcept C105922876 @default.
- W1997735375 hasConcept C1122143 @default.
- W1997735375 hasConcept C126322002 @default.
- W1997735375 hasConcept C27101514 @default.
- W1997735375 hasConcept C2776042228 @default.
- W1997735375 hasConcept C2776954882 @default.
- W1997735375 hasConcept C2777714996 @default.
- W1997735375 hasConcept C2780769369 @default.
- W1997735375 hasConcept C42219234 @default.
- W1997735375 hasConcept C534529494 @default.
- W1997735375 hasConcept C56283660 @default.
- W1997735375 hasConcept C71924100 @default.
- W1997735375 hasConceptScore W1997735375C105922876 @default.
- W1997735375 hasConceptScore W1997735375C1122143 @default.
- W1997735375 hasConceptScore W1997735375C126322002 @default.
- W1997735375 hasConceptScore W1997735375C27101514 @default.
- W1997735375 hasConceptScore W1997735375C2776042228 @default.
- W1997735375 hasConceptScore W1997735375C2776954882 @default.
- W1997735375 hasConceptScore W1997735375C2777714996 @default.
- W1997735375 hasConceptScore W1997735375C2780769369 @default.
- W1997735375 hasConceptScore W1997735375C42219234 @default.
- W1997735375 hasConceptScore W1997735375C534529494 @default.
- W1997735375 hasConceptScore W1997735375C56283660 @default.
- W1997735375 hasConceptScore W1997735375C71924100 @default.
- W1997735375 hasIssue "3" @default.
- W1997735375 hasLocation W19977353751 @default.
- W1997735375 hasLocation W19977353752 @default.
- W1997735375 hasOpenAccess W1997735375 @default.
- W1997735375 hasPrimaryLocation W19977353751 @default.
- W1997735375 hasRelatedWork W1810409014 @default.
- W1997735375 hasRelatedWork W1975703831 @default.
- W1997735375 hasRelatedWork W2000470005 @default.
- W1997735375 hasRelatedWork W2002247332 @default.
- W1997735375 hasRelatedWork W2027374919 @default.
- W1997735375 hasRelatedWork W2066635153 @default.
- W1997735375 hasRelatedWork W2068840900 @default.
- W1997735375 hasRelatedWork W2408994002 @default.
- W1997735375 hasRelatedWork W2415124956 @default.
- W1997735375 hasRelatedWork W2238707306 @default.
- W1997735375 hasVolume "16" @default.
- W1997735375 isParatext "false" @default.
- W1997735375 isRetracted "false" @default.
- W1997735375 magId "1997735375" @default.
- W1997735375 workType "article" @default.