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- W1997738769 abstract "The antigrowth effects of 5 different cloned human leukocyte IFN subtypes (IFN-αA, B, C, D, F) and 2 molecular hybrids between them (IFN-αAD(BglII) and IFN-αDA(BglII)) were examined on 6 different human cell lines. The results indicate that the interferons sort into two distinct groups: IFN-αB, C and F showed comparable antiproliferative activity which was greater than that of IFN-αA, D, AD(BglII) and DA(BglII). The interferons could also be assigned to one of two groups on the basis of their antiviral activity. IFN-αA, D and AD(BglII) were observed to be more protective than IFN-αA, C and F against HSV-2 and EMCV infections, i.e. the relative antiviral efficacies of the cloned IFN subtypes were the reverse of their antiproliferative activities." @default.
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- W1997738769 date "1983-04-01" @default.
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- W1997738769 title "Human leukocyte interferon subtypes have different antiproliferative and antiviral activities on human cells" @default.
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- W1997738769 doi "https://doi.org/10.1016/0006-291x(83)91498-5" @default.
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