FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997756465> ?p ?o ?g. }

• W1997756465 abstract "During the same postnatal period of development when their terminal projection patterns in the midbrain are maturing, lateral superior olivary (LSO) neurons are immunoreactive for serotonin (5-HT). As there is no evidence that LSO neurons synthesize 5-HT, it is likely that they accumulate 5-HT via the 5-HT transporter. To determine if the 5-HT transporter is responsible for 5-HT inside postnatal mouse LSO neurons, pups (postnatal ages 5-6) were treated with fluoxetine and LSO neurons examined for 5-HT. We also evaluated whether LSO neurons containing 5-HT expressed the 5-HT transporter. To further rule out any potential synthesis of 5-HT, brainstem sections of mice at postnatal ages when 5-HT staining is the most robust were stained for the rate-limiting enzyme in the synthesis of 5-HT, tryptophan hydroxylase. Fluoxetine treatment reduced or in most cases, completely eliminated the number of neurons in the LSO stained for 5-HT. Postnatal LSO neurons containing 5-HT were immunoreactive for the 5-HT transporter; in older animals in which 5-HT was no longer observed in the LSO neurons, 5-HT transporter expression was similarly absent. Further, LSO neurons in mice at any age did not stain for tryptophan hydroxylase. These results indicate that LSO neurons express the functional 5-HT transporter to internalize 5-HT; this mechanism may serve to regulate extracellular 5-HT levels during maturation of their terminal endings in the inferior colliculus." @default.
• W1997756465 created "2016-06-24" @default.
• W1997756465 creator A5004798606 @default.
• W1997756465 creator A5042113229 @default.
• W1997756465 date "2009-02-01" @default.
• W1997756465 modified "2023-09-26" @default.
• W1997756465 title "Experimental evidence that the serotonin transporter mediates serotonin accumulation in LSO neurons of the postnatal mouse" @default.
• W1997756465 cites W1204626392 @default.
• W1997756465 cites W1238819995 @default.
• W1997756465 cites W1530652082 @default.
• W1997756465 cites W1713895945 @default.
• W1997756465 cites W1776942521 @default.
• W1997756465 cites W1790719652 @default.
• W1997756465 cites W1871888125 @default.
• W1997756465 cites W1960048350 @default.
• W1997756465 cites W1964036468 @default.
• W1997756465 cites W1965028761 @default.
• W1997756465 cites W1972223203 @default.
• W1997756465 cites W1998084858 @default.
• W1997756465 cites W1998196304 @default.
• W1997756465 cites W2000164063 @default.
• W1997756465 cites W2006522177 @default.
• W1997756465 cites W2008721272 @default.
• W1997756465 cites W2013740680 @default.
• W1997756465 cites W2014711343 @default.
• W1997756465 cites W2018436331 @default.
• W1997756465 cites W2018710515 @default.
• W1997756465 cites W2019351878 @default.
• W1997756465 cites W2031008625 @default.
• W1997756465 cites W2035182425 @default.
• W1997756465 cites W2035412866 @default.
• W1997756465 cites W2042903064 @default.
• W1997756465 cites W2045850697 @default.
• W1997756465 cites W2049842274 @default.
• W1997756465 cites W2051918534 @default.
• W1997756465 cites W2052825559 @default.
• W1997756465 cites W2074071827 @default.
• W1997756465 cites W2079507733 @default.
• W1997756465 cites W2080402976 @default.
• W1997756465 cites W2085125048 @default.
• W1997756465 cites W2085345823 @default.
• W1997756465 cites W2085936836 @default.
• W1997756465 cites W2091923439 @default.
• W1997756465 cites W2092138772 @default.
• W1997756465 cites W2092413568 @default.
• W1997756465 cites W2101382188 @default.
• W1997756465 cites W2106069860 @default.
• W1997756465 cites W2124637051 @default.
• W1997756465 cites W2133375216 @default.
• W1997756465 cites W2136697301 @default.
• W1997756465 cites W2142401824 @default.
• W1997756465 cites W2145914632 @default.
• W1997756465 cites W2163408424 @default.
• W1997756465 cites W2165833361 @default.
• W1997756465 cites W2171264979 @default.
• W1997756465 cites W2501706904 @default.
• W1997756465 cites W2552318961 @default.
• W1997756465 cites W2975947290 @default.
• W1997756465 cites W308514409 @default.
• W1997756465 cites W39784815 @default.
• W1997756465 doi "https://doi.org/10.1016/j.brainres.2008.11.054" @default.
• W1997756465 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19070605" @default.
• W1997756465 hasPublicationYear "2009" @default.
• W1997756465 type Work @default.
• W1997756465 sameAs 1997756465 @default.
• W1997756465 citedByCount "3" @default.
• W1997756465 countsByYear W19977564652016 @default.
• W1997756465 crossrefType "journal-article" @default.
• W1997756465 hasAuthorship W1997756465A5004798606 @default.
• W1997756465 hasAuthorship W1997756465A5042113229 @default.
• W1997756465 hasConcept C104317684 @default.
• W1997756465 hasConcept C126322002 @default.
• W1997756465 hasConcept C134018914 @default.
• W1997756465 hasConcept C149011108 @default.
• W1997756465 hasConcept C169760540 @default.
• W1997756465 hasConcept C170493617 @default.
• W1997756465 hasConcept C2775864247 @default.
• W1997756465 hasConcept C2775951788 @default.
• W1997756465 hasConcept C2776219046 @default.
• W1997756465 hasConcept C2778897192 @default.
• W1997756465 hasConcept C2908747647 @default.
• W1997756465 hasConcept C37000724 @default.
• W1997756465 hasConcept C529278444 @default.
• W1997756465 hasConcept C53910766 @default.
• W1997756465 hasConcept C551621295 @default.
• W1997756465 hasConcept C552161191 @default.
• W1997756465 hasConcept C55493867 @default.
• W1997756465 hasConcept C71924100 @default.
• W1997756465 hasConcept C86803240 @default.
• W1997756465 hasConceptScore W1997756465C104317684 @default.
• W1997756465 hasConceptScore W1997756465C126322002 @default.
• W1997756465 hasConceptScore W1997756465C134018914 @default.
• W1997756465 hasConceptScore W1997756465C149011108 @default.
• W1997756465 hasConceptScore W1997756465C169760540 @default.
• W1997756465 hasConceptScore W1997756465C170493617 @default.
• W1997756465 hasConceptScore W1997756465C2775864247 @default.
• W1997756465 hasConceptScore W1997756465C2775951788 @default.
• W1997756465 hasConceptScore W1997756465C2776219046 @default.
• W1997756465 hasConceptScore W1997756465C2778897192 @default.
• W1997756465 hasConceptScore W1997756465C2908747647 @default.

• next