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- W1997756819 abstract "Desmosterol and beta-sitosterol were esterified when incubated with normal human plasma. The initial rate of demosterol esterification was 1.7 times faster, and that of beta-sitosterol 0.4 times slower, than the esterification rate of cholesterol. These ratios were found to be almost the same when plasma from different normal individuals was tested. Plasma from a patient with familial lecithin:cholesterol acyltransferase deficiency did not esterify any of the sterols. The esterification of desmosterol and beta-sitosterol was considerably slower in normal plasma in which in vitro cholesterol esterification previously had taken place. The different esterification rates could not be explained by a different affinity of the plasma lipoproteins for the sterols tested. Cholecalciferol added to normal plasma did not become esterified." @default.
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- W1997756819 date "1975-01-01" @default.
- W1997756819 modified "2023-09-23" @default.
- W1997756819 title "Substrate Specificity of Lecithin:Cholesterol Acyltransferase Esterification of Desmosterol, β-Sitosterol, and Cholecalciferol in Human Plasma" @default.
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- W1997756819 doi "https://doi.org/10.1080/00365517509095797" @default.
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