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• W1997772711 abstract "Antiretroviral therapy (ART) significantly reduced the CD8 cell noncytotoxic anti-HIV response in 12 HIV-1-infected subjects (P < 0.0001). In separate experiments, CD8(+) cells from long-term survivors were cocultured with HIV-infected CD4(+) cells using varying concentrations of anti-HIV drugs. The antiviral function of CD8(+) cells from 4 of the 14 LTSs was reduced with exposure to 10 μM of nevirapine (P < 0.05). The antiviral activity of CD8(+) cells from 2 LTSs was inhibited by 5 μM of zidovudine. These studies indicate that nevirapine and probably zidovudine can inhibit the anti-HIV activity of CD8(+) cells and thus could influence the effectiveness of antiretroviral therapy." @default.
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• W1997772711 date "2013-06-01" @default.
• W1997772711 modified "2023-09-24" @default.
• W1997772711 title "Nevirapine Inhibits the Anti-HIV Activity of CD8+ Cells" @default.
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• W1997772711 doi "https://doi.org/10.1097/qai.0b013e318289822d" @default.
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