FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997787489> ?p ?o ?g. }

• W1997787489 endingPage "812" @default.
• W1997787489 startingPage "808" @default.
• W1997787489 abstract "Objective To assess the incidence of hemophagocytic lymphohistiocytosis (HLH) in a well-defined population of children with inflammatory bowel disease (IBD) and evaluate the common clinical and laboratory characteristics of individuals with IBD who developed HLH. Study design We conducted a retrospective study of all children who developed HLH over an 8-year period. The incidence of HLH in patients with IBD was calculated using US census data and a statewide project examining the epidemiology of pediatric IBD. Results Among children in Wisconsin, 20 cases of HLH occurred during the study period; 5 cases occurred in children with IBD. Common characteristics include: Crohn's disease (CD), thiopurine administration, fever lasting more than 5 days, lymphadenopathy, splenomegaly, anemia, lymphopenia, and elevated serum triglycerides and ferritin. Of the patients, 4 had primary Epstein-Barr virus infections. The incidence of HLH among all children in Wisconsin was 1.5 per 100 000 per year. The risk was more than 100-fold greater for children with CD (P < .00001). Conclusions Pediatric patients with CD are at increased risk for developing HLH; primary Epstein-Barr virus infection and thiopurine administration may be risk factors. To assess the incidence of hemophagocytic lymphohistiocytosis (HLH) in a well-defined population of children with inflammatory bowel disease (IBD) and evaluate the common clinical and laboratory characteristics of individuals with IBD who developed HLH. We conducted a retrospective study of all children who developed HLH over an 8-year period. The incidence of HLH in patients with IBD was calculated using US census data and a statewide project examining the epidemiology of pediatric IBD. Among children in Wisconsin, 20 cases of HLH occurred during the study period; 5 cases occurred in children with IBD. Common characteristics include: Crohn's disease (CD), thiopurine administration, fever lasting more than 5 days, lymphadenopathy, splenomegaly, anemia, lymphopenia, and elevated serum triglycerides and ferritin. Of the patients, 4 had primary Epstein-Barr virus infections. The incidence of HLH among all children in Wisconsin was 1.5 per 100 000 per year. The risk was more than 100-fold greater for children with CD (P < .00001). Pediatric patients with CD are at increased risk for developing HLH; primary Epstein-Barr virus infection and thiopurine administration may be risk factors." @default.
• W1997787489 created "2016-06-24" @default.
• W1997787489 creator A5006249166 @default.
• W1997787489 creator A5013136717 @default.
• W1997787489 creator A5023837478 @default.
• W1997787489 creator A5024263853 @default.
• W1997787489 creator A5043793286 @default.
• W1997787489 creator A5056146847 @default.
• W1997787489 creator A5065982139 @default.
• W1997787489 date "2011-11-01" @default.
• W1997787489 modified "2023-09-30" @default.
• W1997787489 title "Association of Crohn’s Disease, Thiopurines, and Primary Epstein-Barr Virus Infection with Hemophagocytic Lymphohistiocytosis" @default.
• W1997787489 cites W1517931144 @default.
• W1997787489 cites W1972344313 @default.
• W1997787489 cites W1981679408 @default.
• W1997787489 cites W1985586723 @default.
• W1997787489 cites W2005864535 @default.
• W1997787489 cites W2030539940 @default.
• W1997787489 cites W2036736055 @default.
• W1997787489 cites W2037650755 @default.
• W1997787489 cites W2038911492 @default.
• W1997787489 cites W2046388899 @default.
• W1997787489 cites W2046501733 @default.
• W1997787489 cites W2062369130 @default.
• W1997787489 cites W2062919561 @default.
• W1997787489 cites W2066317932 @default.
• W1997787489 cites W2067041786 @default.
• W1997787489 cites W2073772299 @default.
• W1997787489 cites W2078385666 @default.
• W1997787489 cites W2091907704 @default.
• W1997787489 cites W2092245888 @default.
• W1997787489 cites W2098626256 @default.
• W1997787489 cites W2100450925 @default.
• W1997787489 cites W2103155822 @default.
• W1997787489 cites W2104176524 @default.
• W1997787489 cites W2120231489 @default.
• W1997787489 cites W2135597604 @default.
• W1997787489 cites W2136425428 @default.
• W1997787489 cites W2143232661 @default.
• W1997787489 cites W2144510654 @default.
• W1997787489 cites W2162251899 @default.
• W1997787489 cites W2163247444 @default.
• W1997787489 cites W2171678723 @default.
• W1997787489 cites W2194294435 @default.
• W1997787489 cites W2323865642 @default.
• W1997787489 cites W2332637298 @default.
• W1997787489 cites W2766739355 @default.
• W1997787489 cites W4206437971 @default.
• W1997787489 doi "https://doi.org/10.1016/j.jpeds.2011.04.045" @default.
• W1997787489 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3191286" @default.
• W1997787489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21722918" @default.
• W1997787489 hasPublicationYear "2011" @default.
• W1997787489 type Work @default.
• W1997787489 sameAs 1997787489 @default.
• W1997787489 citedByCount "64" @default.
• W1997787489 countsByYear W19977874892012 @default.
• W1997787489 countsByYear W19977874892013 @default.
• W1997787489 countsByYear W19977874892014 @default.
• W1997787489 countsByYear W19977874892015 @default.
• W1997787489 countsByYear W19977874892016 @default.
• W1997787489 countsByYear W19977874892017 @default.
• W1997787489 countsByYear W19977874892018 @default.
• W1997787489 countsByYear W19977874892019 @default.
• W1997787489 countsByYear W19977874892020 @default.
• W1997787489 countsByYear W19977874892021 @default.
• W1997787489 countsByYear W19977874892022 @default.
• W1997787489 countsByYear W19977874892023 @default.
• W1997787489 crossrefType "journal-article" @default.
• W1997787489 hasAuthorship W1997787489A5006249166 @default.
• W1997787489 hasAuthorship W1997787489A5013136717 @default.
• W1997787489 hasAuthorship W1997787489A5023837478 @default.
• W1997787489 hasAuthorship W1997787489A5024263853 @default.
• W1997787489 hasAuthorship W1997787489A5043793286 @default.
• W1997787489 hasAuthorship W1997787489A5056146847 @default.
• W1997787489 hasAuthorship W1997787489A5065982139 @default.
• W1997787489 hasBestOaLocation W19977874892 @default.
• W1997787489 hasConcept C120665830 @default.
• W1997787489 hasConcept C121332964 @default.
• W1997787489 hasConcept C126322002 @default.
• W1997787489 hasConcept C167135981 @default.
• W1997787489 hasConcept C187212893 @default.
• W1997787489 hasConcept C203014093 @default.
• W1997787489 hasConcept C2778260677 @default.
• W1997787489 hasConcept C2779079688 @default.
• W1997787489 hasConcept C2779134260 @default.
• W1997787489 hasConcept C2779280984 @default.
• W1997787489 hasConcept C2780479503 @default.
• W1997787489 hasConcept C2908647359 @default.
• W1997787489 hasConcept C61511704 @default.
• W1997787489 hasConcept C70917649 @default.
• W1997787489 hasConcept C71924100 @default.
• W1997787489 hasConcept C99454951 @default.
• W1997787489 hasConceptScore W1997787489C120665830 @default.
• W1997787489 hasConceptScore W1997787489C121332964 @default.
• W1997787489 hasConceptScore W1997787489C126322002 @default.
• W1997787489 hasConceptScore W1997787489C167135981 @default.
• W1997787489 hasConceptScore W1997787489C187212893 @default.
• W1997787489 hasConceptScore W1997787489C203014093 @default.

• next