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- W1997788217 abstract "OBJECTIVE: This study was aimed to assess the effect of the endometrial movement on pregnancy achievement in women receiving ovulation induction by clomiphene citrate followed by intrauterine insemination (IUI).DESIGN: Prospective clinical study.MATERIALS AND METHODS: The study population was composed of all infertile couples without any known factor who were to undergo first-time IUI with clomiphene citrate in Fertility Center of CHA University between September 2008 and January 2009. Not only endometrial movements measured using ultrasound (Accuvix, Medison), but also thickness, volume, pattern, and echogenic change of endometrium were analyzed in prediction of pregnancy.RESULTS: The total number of 241 cycles of IUI with 49 intrauterine pregnancies (20.3%) was analyzed, among the total number of 243 cycles of IUI with 51 clinical pregnancies (21.0%) with 2 cycles of tubal pregnancies. Pregnancy was not related to endometrial thickness and endometrial volume, but significantly related to endometrial movement, trilaminar pattern, and hyperechoic change (p<0.05). Endomtrial movements over than 4 times per minute and with weak or moderate intensity were significantly related to pregnancy (p < 0.05). The major direction of endometrial movement was cervicofundal (82.6%), and hence pregnant group showed higher cervicofundal movement rate as well (89.8% vs 75.5%).CONCLUSIONS: Endometrial movement could be a predictor of pregnancy in IUI cycles. Differently from spontaneous cycles, fundocervical endometrial movement which is retrograde for favorable sperm transport can be overcome by IUI procedures. OBJECTIVE: This study was aimed to assess the effect of the endometrial movement on pregnancy achievement in women receiving ovulation induction by clomiphene citrate followed by intrauterine insemination (IUI). DESIGN: Prospective clinical study. MATERIALS AND METHODS: The study population was composed of all infertile couples without any known factor who were to undergo first-time IUI with clomiphene citrate in Fertility Center of CHA University between September 2008 and January 2009. Not only endometrial movements measured using ultrasound (Accuvix, Medison), but also thickness, volume, pattern, and echogenic change of endometrium were analyzed in prediction of pregnancy. RESULTS: The total number of 241 cycles of IUI with 49 intrauterine pregnancies (20.3%) was analyzed, among the total number of 243 cycles of IUI with 51 clinical pregnancies (21.0%) with 2 cycles of tubal pregnancies. Pregnancy was not related to endometrial thickness and endometrial volume, but significantly related to endometrial movement, trilaminar pattern, and hyperechoic change (p<0.05). Endomtrial movements over than 4 times per minute and with weak or moderate intensity were significantly related to pregnancy (p < 0.05). The major direction of endometrial movement was cervicofundal (82.6%), and hence pregnant group showed higher cervicofundal movement rate as well (89.8% vs 75.5%). CONCLUSIONS: Endometrial movement could be a predictor of pregnancy in IUI cycles. Differently from spontaneous cycles, fundocervical endometrial movement which is retrograde for favorable sperm transport can be overcome by IUI procedures." @default.
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- W1997788217 date "2009-09-01" @default.
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- W1997788217 title "Can endometrial movements affect the pregnancy rate in IUI cycles?" @default.
- W1997788217 doi "https://doi.org/10.1016/j.fertnstert.2009.07.188" @default.
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