Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997800016> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W1997800016 endingPage "355A" @default.
- W1997800016 startingPage "355A" @default.
- W1997800016 abstract "Ischemic preconditioning (PC) with 5-min ischemia(l) and reperiusion (R) limits infarct size (IS) after subsequent I in rabbits. The aim of this study was to evaluate whether PC with longer I was also protective. Open chest rabbits underwent 30-min occlusion of coronary artery and 48-hrs R. PC was elicited by either a preceding 5-, 10- or 15-min I followed by 5-min R. Additional group underwent 15-min 1& 48-hrs R. IS was measured histologically and expressed as a percentage of the area at risk (AAR).GroupAAR(%LV)IS (%LV)IS (%AAR)non-PC (n = 15)26.7 ± 2.111.1 ± 1.540.1 ± 3.85-min PC (n = 10)26.7 ± 2.73.1 ± 1.0*10.4 ± 2.9*10-min PC (n = 10)28.4 ± 3.13.5 ± 0.9*11.7 ± 2.4*15-min PC(n = 15)25.S ± 1.820.1 ± 1.9*#b77.4 ± 3.7*#b15-min I (n = 10)2S.3 ± 3.85.4 ± 1.0*18.3 ± 1.0**p < 0.05 vs. non-PC#p < 0.05 vs. 5 min PCbp < 0.05 vs. 10 min PC p < 0.05 vs. non-PC p < 0.05 vs. 5 min PC p < 0.05 vs. 10 min PC Since 15-min I caused infarct (18% of AAR). IS caused by test I per se in 15-min PC group was 59.5 ± 3.7% of AAR (p < 0.05 vs. non PC). Thus, PC with 10-min I is as protective as that with 5-min I. However, PC with 15-min I accelerated myocyte necrosis during subsequent I. We conclude that ischemic duration of PC is a determinant of its cardioprotection, and PC with too long ischemia is not protective but harmful." @default.
- W1997800016 created "2016-06-24" @default.
- W1997800016 creator A5006485588 @default.
- W1997800016 creator A5031619898 @default.
- W1997800016 creator A5075795337 @default.
- W1997800016 creator A5077773904 @default.
- W1997800016 creator A5082743149 @default.
- W1997800016 creator A5088306462 @default.
- W1997800016 date "1995-02-01" @default.
- W1997800016 modified "2023-10-16" @default.
- W1997800016 title "1005-76 Preconditioning with 15-min Ischemia Extends Myocardial Infarct Size After Subsequent 30-min Ischemia in Rabbits" @default.
- W1997800016 doi "https://doi.org/10.1016/0735-1097(95)92928-x" @default.
- W1997800016 hasPublicationYear "1995" @default.
- W1997800016 type Work @default.
- W1997800016 sameAs 1997800016 @default.
- W1997800016 citedByCount "3" @default.
- W1997800016 crossrefType "journal-article" @default.
- W1997800016 hasAuthorship W1997800016A5006485588 @default.
- W1997800016 hasAuthorship W1997800016A5031619898 @default.
- W1997800016 hasAuthorship W1997800016A5075795337 @default.
- W1997800016 hasAuthorship W1997800016A5077773904 @default.
- W1997800016 hasAuthorship W1997800016A5082743149 @default.
- W1997800016 hasAuthorship W1997800016A5088306462 @default.
- W1997800016 hasBestOaLocation W19978000162 @default.
- W1997800016 hasConcept C126322002 @default.
- W1997800016 hasConcept C164705383 @default.
- W1997800016 hasConcept C2776268601 @default.
- W1997800016 hasConcept C2779311647 @default.
- W1997800016 hasConcept C2780393670 @default.
- W1997800016 hasConcept C2989005 @default.
- W1997800016 hasConcept C42219234 @default.
- W1997800016 hasConcept C500558357 @default.
- W1997800016 hasConcept C541997718 @default.
- W1997800016 hasConcept C71924100 @default.
- W1997800016 hasConceptScore W1997800016C126322002 @default.
- W1997800016 hasConceptScore W1997800016C164705383 @default.
- W1997800016 hasConceptScore W1997800016C2776268601 @default.
- W1997800016 hasConceptScore W1997800016C2779311647 @default.
- W1997800016 hasConceptScore W1997800016C2780393670 @default.
- W1997800016 hasConceptScore W1997800016C2989005 @default.
- W1997800016 hasConceptScore W1997800016C42219234 @default.
- W1997800016 hasConceptScore W1997800016C500558357 @default.
- W1997800016 hasConceptScore W1997800016C541997718 @default.
- W1997800016 hasConceptScore W1997800016C71924100 @default.
- W1997800016 hasIssue "2" @default.
- W1997800016 hasLocation W19978000161 @default.
- W1997800016 hasLocation W19978000162 @default.
- W1997800016 hasOpenAccess W1997800016 @default.
- W1997800016 hasPrimaryLocation W19978000161 @default.
- W1997800016 hasRelatedWork W112107873 @default.
- W1997800016 hasRelatedWork W193119963 @default.
- W1997800016 hasRelatedWork W1988934442 @default.
- W1997800016 hasRelatedWork W2086714446 @default.
- W1997800016 hasRelatedWork W2132494613 @default.
- W1997800016 hasRelatedWork W2146217294 @default.
- W1997800016 hasRelatedWork W2278555374 @default.
- W1997800016 hasRelatedWork W3144297661 @default.
- W1997800016 hasRelatedWork W3146747982 @default.
- W1997800016 hasRelatedWork W3148438718 @default.
- W1997800016 hasVolume "25" @default.
- W1997800016 isParatext "false" @default.
- W1997800016 isRetracted "false" @default.
- W1997800016 magId "1997800016" @default.
- W1997800016 workType "article" @default.