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- W1997811561 abstract "Abstract The synthesis of chiral γ‐keto bisphosphonates is described. Michael addition of cyclic ketones to vinyl gem ‐bisphosphonate catalyzed by 0.1 mol equiv. ( S )‐(+)‐1‐(2‐pyrrolidinyl)pyrrolidine and benzoic acid gave the products in yields of up to 86 %, dr ( cis / trans ) > 1:99 and ee of up to 99 %. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)" @default.
- W1997811561 created "2016-06-24" @default.
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- W1997811561 date "2008-05-01" @default.
- W1997811561 modified "2023-10-17" @default.
- W1997811561 title "Enamine Catalysis in the Synthesis of Chiral Structural Analogues of <i>gem</i>‐Bisphosphonates Known To Be Biologically Active" @default.
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- W1997811561 doi "https://doi.org/10.1002/ejoc.200800170" @default.
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