FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997824093> ?p ?o ?g. }

• W1997824093 endingPage "247" @default.
• W1997824093 startingPage "237" @default.
• W1997824093 abstract "1. Long-term potentiation (LTP) and depression (LTD) were investigated at synapses formed by pairs of monosynaptically connected CA3 pyramidal cells in rat hippocampal slice cultures. 2. An N-methyl-D-aspartate (NMDA) receptor-mediated component of the unitary EPSP, elicited at the resting membrane potential in response to single action potentials in an individual CA3 cell, could be isolated pharmacologically. 3. Associative LTP was induced when single presynaptic action potentials were repeatedly paired with 240 ms postsynaptic depolarizing pulses that evoked five to twelve action potentials or with single postsynaptic action potentials evoked near the peak of the unitary EPSP. LTP induction was prevented by an NMDA receptor antagonist. 4. Associative LTD was induced when single presynaptic action potentials were repeatedly elicited with a certain delay after either 240 ms postsynaptic depolarizing pulses or single postsynaptic action potentials. The time window within which presynaptic activity had to occur for LTD induction was dependent on the amount of postsynaptic depolarization. LTD was induced if single pre- and postsynaptic action potentials occurred synchronously. 5. Homosynaptic LTD was induced by 3 Hz tetanization of the presynaptic neuron for 3 min and was blocked by an NMDA receptor antagonist. 6. Depotentiation was produced with stimulation protocols that elicit either homosynaptic or associative LTD. 7. Recurrent excitatory synapses between CA3 cells display associative potentiation and depression. The sign of the change in synaptic strength is a function of the relative timing of pre- and postsynaptic action potentials." @default.
• W1997824093 created "2016-06-24" @default.
• W1997824093 creator A5028162083 @default.
• W1997824093 creator A5037126383 @default.
• W1997824093 creator A5049020593 @default.
• W1997824093 date "1998-02-01" @default.
• W1997824093 modified "2023-10-01" @default.
• W1997824093 title "Long-term synaptic plasticity between pairs of individual CA3 pyramidal cells in rat hippocampal slice cultures" @default.
• W1997824093 cites W1521633888 @default.
• W1997824093 cites W1733248925 @default.
• W1997824093 cites W1951222626 @default.
• W1997824093 cites W1966867248 @default.
• W1997824093 cites W1967745586 @default.
• W1997824093 cites W1970053578 @default.
• W1997824093 cites W1972057413 @default.
• W1997824093 cites W1976496829 @default.
• W1997824093 cites W1976738367 @default.
• W1997824093 cites W1978513489 @default.
• W1997824093 cites W1982270009 @default.
• W1997824093 cites W1982937689 @default.
• W1997824093 cites W1995054580 @default.
• W1997824093 cites W2004725045 @default.
• W1997824093 cites W2017743417 @default.
• W1997824093 cites W2028744261 @default.
• W1997824093 cites W2036773579 @default.
• W1997824093 cites W2046388858 @default.
• W1997824093 cites W2052029516 @default.
• W1997824093 cites W2052515926 @default.
• W1997824093 cites W2058709617 @default.
• W1997824093 cites W2061405268 @default.
• W1997824093 cites W2062243367 @default.
• W1997824093 cites W2071290167 @default.
• W1997824093 cites W2072233684 @default.
• W1997824093 cites W2073055671 @default.
• W1997824093 cites W2073772517 @default.
• W1997824093 cites W2082660315 @default.
• W1997824093 cites W2083380998 @default.
• W1997824093 cites W2087642862 @default.
• W1997824093 cites W2097874632 @default.
• W1997824093 cites W2119051448 @default.
• W1997824093 cites W2153564253 @default.
• W1997824093 cites W2164378713 @default.
• W1997824093 cites W2171336978 @default.
• W1997824093 cites W2171796285 @default.
• W1997824093 cites W2335982188 @default.
• W1997824093 cites W2396598205 @default.
• W1997824093 cites W2185212694 @default.
• W1997824093 doi "https://doi.org/10.1111/j.1469-7793.1998.237bu.x" @default.
• W1997824093 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2230782" @default.
• W1997824093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9490845" @default.
• W1997824093 hasPublicationYear "1998" @default.
• W1997824093 type Work @default.
• W1997824093 sameAs 1997824093 @default.
• W1997824093 citedByCount "524" @default.
• W1997824093 countsByYear W19978240932012 @default.
• W1997824093 countsByYear W19978240932013 @default.
• W1997824093 countsByYear W19978240932014 @default.
• W1997824093 countsByYear W19978240932015 @default.
• W1997824093 countsByYear W19978240932016 @default.
• W1997824093 countsByYear W19978240932017 @default.
• W1997824093 countsByYear W19978240932018 @default.
• W1997824093 countsByYear W19978240932019 @default.
• W1997824093 countsByYear W19978240932020 @default.
• W1997824093 countsByYear W19978240932021 @default.
• W1997824093 countsByYear W19978240932022 @default.
• W1997824093 countsByYear W19978240932023 @default.
• W1997824093 crossrefType "journal-article" @default.
• W1997824093 hasAuthorship W1997824093A5028162083 @default.
• W1997824093 hasAuthorship W1997824093A5037126383 @default.
• W1997824093 hasAuthorship W1997824093A5049020593 @default.
• W1997824093 hasBestOaLocation W19978240931 @default.
• W1997824093 hasConcept C112592302 @default.
• W1997824093 hasConcept C118232355 @default.
• W1997824093 hasConcept C12554922 @default.
• W1997824093 hasConcept C160268369 @default.
• W1997824093 hasConcept C169760540 @default.
• W1997824093 hasConcept C170493617 @default.
• W1997824093 hasConcept C17077164 @default.
• W1997824093 hasConcept C185592680 @default.
• W1997824093 hasConcept C197341189 @default.
• W1997824093 hasConcept C25274449 @default.
• W1997824093 hasConcept C2776328245 @default.
• W1997824093 hasConcept C4141045 @default.
• W1997824093 hasConcept C55493867 @default.
• W1997824093 hasConcept C67018056 @default.
• W1997824093 hasConcept C73009533 @default.
• W1997824093 hasConcept C86803240 @default.
• W1997824093 hasConcept C98229152 @default.
• W1997824093 hasConceptScore W1997824093C112592302 @default.
• W1997824093 hasConceptScore W1997824093C118232355 @default.
• W1997824093 hasConceptScore W1997824093C12554922 @default.
• W1997824093 hasConceptScore W1997824093C160268369 @default.
• W1997824093 hasConceptScore W1997824093C169760540 @default.
• W1997824093 hasConceptScore W1997824093C170493617 @default.
• W1997824093 hasConceptScore W1997824093C17077164 @default.
• W1997824093 hasConceptScore W1997824093C185592680 @default.
• W1997824093 hasConceptScore W1997824093C197341189 @default.
• W1997824093 hasConceptScore W1997824093C25274449 @default.

• next