FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997886044> ?p ?o ?g. }

• W1997886044 endingPage "182" @default.
• W1997886044 startingPage "177" @default.
• W1997886044 abstract "Bio-guided fractionation of the total MeOH extract (TME) of the aerial parts of Blepharis ciliaris (L.) B.L. Burtt. (Acanthaceae) growing in Saudi Arabia was carried out to evaluate its hepatoprotective activity against CCl4-induced hepatotoxicity in rats. Successive chromatographic separations of the potent hepatoprotective n-BuOH fraction afforded two new flavonol glycosides, blepharisides A (1) and B (2), along with quercetin 3-O-rutinoside (3). Their structures were established by UV, IR, 1D, 2D NMR, and HRESIMS spectral data, in addition to comparison with literature data. Co-treatment of CCl4 hepatic injured rats with the total MeOH extract (TME) and its fractions significantly restored the hepatic marker enzymes and total bilirubin to near-normal values compared to silymarin (reference drug). The isolated compounds were evaluated for their antioxidant and anti-inflammatory activities. They displayed significant antioxidant activity (DPPH assay) in relation to propyl gallate (positive control) (% inhibition of 88.2, 87.9, and 74.2, respectively). Compounds 1 and 2 demonstrated anti-inflammatory effects in the carrageenin induced paw edema method at a dose of 10 mg/kg." @default.
• W1997886044 created "2016-06-24" @default.
• W1997886044 creator A5006745642 @default.
• W1997886044 creator A5013907723 @default.
• W1997886044 creator A5025580763 @default.
• W1997886044 creator A5031165232 @default.
• W1997886044 creator A5031750600 @default.
• W1997886044 creator A5044935938 @default.
• W1997886044 creator A5062196942 @default.
• W1997886044 date "2015-03-01" @default.
• W1997886044 modified "2023-10-05" @default.
• W1997886044 title "Blepharisides A and B, new flavonol glycosides from Blepharis ciliaris growing in Saudi Arabia" @default.
• W1997886044 cites W1499850422 @default.
• W1997886044 cites W1963500960 @default.
• W1997886044 cites W1966500534 @default.
• W1997886044 cites W1979995322 @default.
• W1997886044 cites W1990583565 @default.
• W1997886044 cites W2001326496 @default.
• W1997886044 cites W2013788800 @default.
• W1997886044 cites W2021905887 @default.
• W1997886044 cites W2031690762 @default.
• W1997886044 cites W2048695976 @default.
• W1997886044 cites W2061040307 @default.
• W1997886044 cites W2072163165 @default.
• W1997886044 cites W2079375070 @default.
• W1997886044 cites W2106010597 @default.
• W1997886044 cites W2110373755 @default.
• W1997886044 cites W2125299541 @default.
• W1997886044 cites W2157565326 @default.
• W1997886044 cites W2171968926 @default.
• W1997886044 doi "https://doi.org/10.1016/j.phytol.2014.12.018" @default.
• W1997886044 hasPublicationYear "2015" @default.
• W1997886044 type Work @default.
• W1997886044 sameAs 1997886044 @default.
• W1997886044 citedByCount "18" @default.
• W1997886044 countsByYear W19978860442015 @default.
• W1997886044 countsByYear W19978860442016 @default.
• W1997886044 countsByYear W19978860442017 @default.
• W1997886044 countsByYear W19978860442018 @default.
• W1997886044 countsByYear W19978860442019 @default.
• W1997886044 countsByYear W19978860442020 @default.
• W1997886044 countsByYear W19978860442021 @default.
• W1997886044 countsByYear W19978860442022 @default.
• W1997886044 countsByYear W19978860442023 @default.
• W1997886044 crossrefType "journal-article" @default.
• W1997886044 hasAuthorship W1997886044A5006745642 @default.
• W1997886044 hasAuthorship W1997886044A5013907723 @default.
• W1997886044 hasAuthorship W1997886044A5025580763 @default.
• W1997886044 hasAuthorship W1997886044A5031165232 @default.
• W1997886044 hasAuthorship W1997886044A5031750600 @default.
• W1997886044 hasAuthorship W1997886044A5044935938 @default.
• W1997886044 hasAuthorship W1997886044A5062196942 @default.
• W1997886044 hasConcept C102124568 @default.
• W1997886044 hasConcept C178790620 @default.
• W1997886044 hasConcept C185592680 @default.
• W1997886044 hasConcept C194671627 @default.
• W1997886044 hasConcept C2777359374 @default.
• W1997886044 hasConcept C2777505162 @default.
• W1997886044 hasConcept C2778004101 @default.
• W1997886044 hasConcept C2779703632 @default.
• W1997886044 hasConcept C2781263971 @default.
• W1997886044 hasConcept C2781401929 @default.
• W1997886044 hasConcept C43617362 @default.
• W1997886044 hasConcept C55493867 @default.
• W1997886044 hasConcept C556039675 @default.
• W1997886044 hasConcept C71240020 @default.
• W1997886044 hasConcept C71924100 @default.
• W1997886044 hasConcept C86803240 @default.
• W1997886044 hasConcept C97428945 @default.
• W1997886044 hasConcept C98274493 @default.
• W1997886044 hasConceptScore W1997886044C102124568 @default.
• W1997886044 hasConceptScore W1997886044C178790620 @default.
• W1997886044 hasConceptScore W1997886044C185592680 @default.
• W1997886044 hasConceptScore W1997886044C194671627 @default.
• W1997886044 hasConceptScore W1997886044C2777359374 @default.
• W1997886044 hasConceptScore W1997886044C2777505162 @default.
• W1997886044 hasConceptScore W1997886044C2778004101 @default.
• W1997886044 hasConceptScore W1997886044C2779703632 @default.
• W1997886044 hasConceptScore W1997886044C2781263971 @default.
• W1997886044 hasConceptScore W1997886044C2781401929 @default.
• W1997886044 hasConceptScore W1997886044C43617362 @default.
• W1997886044 hasConceptScore W1997886044C55493867 @default.
• W1997886044 hasConceptScore W1997886044C556039675 @default.
• W1997886044 hasConceptScore W1997886044C71240020 @default.
• W1997886044 hasConceptScore W1997886044C71924100 @default.
• W1997886044 hasConceptScore W1997886044C86803240 @default.
• W1997886044 hasConceptScore W1997886044C97428945 @default.
• W1997886044 hasConceptScore W1997886044C98274493 @default.
• W1997886044 hasLocation W19978860441 @default.
• W1997886044 hasOpenAccess W1997886044 @default.
• W1997886044 hasPrimaryLocation W19978860441 @default.
• W1997886044 hasRelatedWork W2108465548 @default.
• W1997886044 hasRelatedWork W2376642984 @default.
• W1997886044 hasRelatedWork W2381885610 @default.
• W1997886044 hasRelatedWork W2393239249 @default.
• W1997886044 hasRelatedWork W2617523712 @default.
• W1997886044 hasRelatedWork W2764841094 @default.
• W1997886044 hasRelatedWork W2893677820 @default.

• next