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- W1997886263 abstract "Leucocidins and gamma-hemolysins are bi-component staphylococcal toxins that form lytic transmembrane pores. Their cytotoxic activities involve the synergistic association of a class S and a class F component, produced as water-soluble monomers which assemble on the surface of specific cells. The structure of the F protein from Panton-Valentine leucocidin, solved at 2.0 A resolution, and sequence alignment suggest that it represents the fold of any secreted protein in this family of toxins. The comparison of this structure to that of the homoheptameric alpha-hemolysin provides some insights into the molecular events that may occur during pore formation." @default.
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- W1997886263 date "2000-10-01" @default.
- W1997886263 modified "2023-09-25" @default.
- W1997886263 title "Crystal structure of the F component of the Panton-Valentine leucocidin" @default.
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- W1997886263 doi "https://doi.org/10.1016/s1438-4221(00)80050-8" @default.
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