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• W1997892137 abstract "The present study reports the potential anti-rheumatoid activity of Panax ginseng head part. P. ginseng-head part BuOH fraction (PGHB) was safe in acute toxicity (LD50 > 5000 mg/kg) and inhibited the partially acetic acid-induced writhes (approximately 32%, P < 0.05) in mice. PGHB (500 mg/kg) inhibited the acetic acid-induced extravasation of Evan’s blue dye in mice by approximately 20.6% (P < 0.05), and was similar to the suppressive effect of ibuprofen (27.7%) as a positive control drug. Also, PGHB reduced the carrageenan-induced paw edema at 3 h after oral administration, and suppressed the production of serum IL-6 in CIA mice. This suggests that PGHB has potential analgesic and anti-inflammatory activities, and will be the supporting evidence for the potential anti-rheumatoid activity of Korean P. ginseng-head." @default.
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• W1997892137 date "2008-12-01" @default.
• W1997892137 modified "2023-10-12" @default.
• W1997892137 title "Potential analgesic and anti-inflammatory activities of Panax ginseng head butanolic fraction in animals" @default.
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• W1997892137 doi "https://doi.org/10.1016/j.fct.2008.09.055" @default.
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