FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997978980> ?p ?o ?g. }

• W1997978980 endingPage "e37837" @default.
• W1997978980 startingPage "e37837" @default.
• W1997978980 abstract "Background The relationship between hypertension and kidney disease is complicated. Clinical trials found intense blood pressure control was not associated with alterations in glomerular filtration rate (GFR) in all patients but did slow the rate of GFR decline among those with a higher baseline proteinuria. However, the underlying mechanism has been unclear. Methods We tested the hypothesis that the association between high blood pressure and renal function is modified by albuminuria status by conducting analyses in a cross-sectional study with 12,440 adult participants without known kidney diseases, diabetes or cardiovascular diseases, participating in the National Health and Nutrition Examination Survey (NHANES) 1999–2006. Results 1226 out of 12440 were found to have unknown high blood pressure and 4494 were found to have reduced renal function. Overall, a moderate association was found between high blood pressure and renal function insufficiency in all participants analyzed. However, among participants with albuminuria, the prevalence of moderate-severe renal insufficiency substantially and progressively increased from normal subjects to prehypertensive and undiagnosed hypertensive subjects (1.43%, 3.44%, 10.96%, respectively, P for trend<0.0001); on the other hand, the prevalence of undiagnosed hypertension was also significantly higher among subjects with moderate-severe renal insufficiency than those with mild renal insufficiency (35.54% Vs 19.09%, P value <0.05), supporting an association between hypertension and renal function damage. In contrast, no association between hypertension and renal insufficiency was observed among those without albuminuria in this population. Similar findings were observed when the CKD-EPI equation was used. Conclusions The association between high blood pressure and reduced renal function could be dependent upon the albuminuria status. This finding may provide a possible explanation for results observed in clinical trials of intensive blood pressure control. Further studies are warranted to confirm our findings." @default.
• W1997978980 created "2016-06-24" @default.
• W1997978980 creator A5001198279 @default.
• W1997978980 creator A5019544133 @default.
• W1997978980 creator A5030538673 @default.
• W1997978980 creator A5035695257 @default.
• W1997978980 creator A5042782798 @default.
• W1997978980 creator A5048018294 @default.
• W1997978980 creator A5050712578 @default.
• W1997978980 creator A5056193431 @default.
• W1997978980 creator A5061543677 @default.
• W1997978980 date "2012-07-03" @default.
• W1997978980 modified "2023-09-27" @default.
• W1997978980 title "Association of High Blood Pressure with Renal Insufficiency: Role of Albuminuria, from NHANES, 1999–2006" @default.
• W1997978980 cites W1939988777 @default.
• W1997978980 cites W1982920623 @default.
• W1997978980 cites W1990397156 @default.
• W1997978980 cites W1996256106 @default.
• W1997978980 cites W2004384131 @default.
• W1997978980 cites W2005370325 @default.
• W1997978980 cites W2007931956 @default.
• W1997978980 cites W2009517244 @default.
• W1997978980 cites W2017286178 @default.
• W1997978980 cites W2038971810 @default.
• W1997978980 cites W2043159810 @default.
• W1997978980 cites W2043575472 @default.
• W1997978980 cites W2044178472 @default.
• W1997978980 cites W2045516356 @default.
• W1997978980 cites W2047390341 @default.
• W1997978980 cites W2048811560 @default.
• W1997978980 cites W2049428559 @default.
• W1997978980 cites W2065980221 @default.
• W1997978980 cites W2072869822 @default.
• W1997978980 cites W2073742622 @default.
• W1997978980 cites W2075391935 @default.
• W1997978980 cites W2076980406 @default.
• W1997978980 cites W2078800559 @default.
• W1997978980 cites W2089395529 @default.
• W1997978980 cites W2104443849 @default.
• W1997978980 cites W2116077357 @default.
• W1997978980 cites W2117714489 @default.
• W1997978980 cites W2118992949 @default.
• W1997978980 cites W2120235169 @default.
• W1997978980 cites W2123196786 @default.
• W1997978980 cites W2125089162 @default.
• W1997978980 cites W2134422033 @default.
• W1997978980 cites W2136145230 @default.
• W1997978980 cites W2139804390 @default.
• W1997978980 cites W2141269765 @default.
• W1997978980 cites W2143954917 @default.
• W1997978980 cites W2155965977 @default.
• W1997978980 cites W2167142042 @default.
• W1997978980 cites W2321986725 @default.
• W1997978980 cites W2488868277 @default.
• W1997978980 doi "https://doi.org/10.1371/journal.pone.0037837" @default.
• W1997978980 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3388992" @default.
• W1997978980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22802927" @default.
• W1997978980 hasPublicationYear "2012" @default.
• W1997978980 type Work @default.
• W1997978980 sameAs 1997978980 @default.
• W1997978980 citedByCount "14" @default.
• W1997978980 countsByYear W19979789802013 @default.
• W1997978980 countsByYear W19979789802014 @default.
• W1997978980 countsByYear W19979789802016 @default.
• W1997978980 countsByYear W19979789802017 @default.
• W1997978980 countsByYear W19979789802020 @default.
• W1997978980 countsByYear W19979789802022 @default.
• W1997978980 crossrefType "journal-article" @default.
• W1997978980 hasAuthorship W1997978980A5001198279 @default.
• W1997978980 hasAuthorship W1997978980A5019544133 @default.
• W1997978980 hasAuthorship W1997978980A5030538673 @default.
• W1997978980 hasAuthorship W1997978980A5035695257 @default.
• W1997978980 hasAuthorship W1997978980A5042782798 @default.
• W1997978980 hasAuthorship W1997978980A5048018294 @default.
• W1997978980 hasAuthorship W1997978980A5050712578 @default.
• W1997978980 hasAuthorship W1997978980A5056193431 @default.
• W1997978980 hasAuthorship W1997978980A5061543677 @default.
• W1997978980 hasBestOaLocation W19979789801 @default.
• W1997978980 hasConcept C118190526 @default.
• W1997978980 hasConcept C126322002 @default.
• W1997978980 hasConcept C134018914 @default.
• W1997978980 hasConcept C159641895 @default.
• W1997978980 hasConcept C164705383 @default.
• W1997978980 hasConcept C2776174234 @default.
• W1997978980 hasConcept C2778653478 @default.
• W1997978980 hasConcept C2779561371 @default.
• W1997978980 hasConcept C2779874844 @default.
• W1997978980 hasConcept C2780091579 @default.
• W1997978980 hasConcept C2908647359 @default.
• W1997978980 hasConcept C555293320 @default.
• W1997978980 hasConcept C71924100 @default.
• W1997978980 hasConcept C84393581 @default.
• W1997978980 hasConcept C99454951 @default.
• W1997978980 hasConceptScore W1997978980C118190526 @default.
• W1997978980 hasConceptScore W1997978980C126322002 @default.
• W1997978980 hasConceptScore W1997978980C134018914 @default.
• W1997978980 hasConceptScore W1997978980C159641895 @default.
• W1997978980 hasConceptScore W1997978980C164705383 @default.

• next