Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997992449> ?p ?o ?g. }
- W1997992449 endingPage "82" @default.
- W1997992449 startingPage "76" @default.
- W1997992449 abstract "Diabetic retinopathy is the leading cause of blindness in the working population of the developed countries and also a significant cause of blindness in the elderly. This study aimed at examining the protective effect of H(2) saline on diabetic retinopathy in a streptozotocin-induced diabetic rat model.Sprague-Dawley male rats were divided into 3 groups as follows: (1) nondiabetic control group (non-DM control); (2) diabetic control group (DM control); and (3) diabetic rats receiving H(2) saline therapy (DM H(2) saline). Rats in DM H(2) saline group were intraperitoneally injected with H(2) saturated saline (5 mL/kg) every day for 4 weeks. Retinal vascular permeability was assessed by measuring Evans blue leakage into the retina. Retinal apoptosis was evaluated by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining and measuring caspase-3 activity. Retinal thickness was observed by hematoxylin and eosin staining.Our results showed that H(2) saline treatment could depress the caspase activity, reduce the retinal apoptosis, and vascular permeability. The H(2) saline could also prominently attenuate the retinal parenchyma thickening that resulted from diabetic retinopathy.Our preliminary studies indicated that H(2) saline may have potentials in the clinical treatment of diabetic retinopathy." @default.
- W1997992449 created "2016-06-24" @default.
- W1997992449 creator A5003065832 @default.
- W1997992449 creator A5009247381 @default.
- W1997992449 creator A5044475287 @default.
- W1997992449 creator A5048313363 @default.
- W1997992449 creator A5071924058 @default.
- W1997992449 creator A5074094867 @default.
- W1997992449 creator A5074581152 @default.
- W1997992449 creator A5075981348 @default.
- W1997992449 creator A5087962830 @default.
- W1997992449 date "2012-02-01" @default.
- W1997992449 modified "2023-09-30" @default.
- W1997992449 title "Protective Effects of Hydrogen Saline on Diabetic Retinopathy in a Streptozotocin-Induced Diabetic Rat Model" @default.
- W1997992449 cites W1515993630 @default.
- W1997992449 cites W1963789809 @default.
- W1997992449 cites W1968170469 @default.
- W1997992449 cites W1988917929 @default.
- W1997992449 cites W1993968665 @default.
- W1997992449 cites W1996478420 @default.
- W1997992449 cites W2005767645 @default.
- W1997992449 cites W2010962252 @default.
- W1997992449 cites W2021213106 @default.
- W1997992449 cites W2021338387 @default.
- W1997992449 cites W2023126647 @default.
- W1997992449 cites W2028765929 @default.
- W1997992449 cites W2030315827 @default.
- W1997992449 cites W2040087338 @default.
- W1997992449 cites W2041137175 @default.
- W1997992449 cites W2043243208 @default.
- W1997992449 cites W2043393337 @default.
- W1997992449 cites W2044437167 @default.
- W1997992449 cites W2053588089 @default.
- W1997992449 cites W2057683168 @default.
- W1997992449 cites W2058983290 @default.
- W1997992449 cites W2066344747 @default.
- W1997992449 cites W2072157209 @default.
- W1997992449 cites W2075008661 @default.
- W1997992449 cites W2075627766 @default.
- W1997992449 cites W2075764309 @default.
- W1997992449 cites W2081535097 @default.
- W1997992449 cites W2091261755 @default.
- W1997992449 cites W2115337518 @default.
- W1997992449 cites W2121784482 @default.
- W1997992449 cites W2124098523 @default.
- W1997992449 cites W2134954483 @default.
- W1997992449 cites W2149239535 @default.
- W1997992449 cites W2168795718 @default.
- W1997992449 cites W2169657429 @default.
- W1997992449 cites W2171994468 @default.
- W1997992449 cites W2172356054 @default.
- W1997992449 cites W2434989288 @default.
- W1997992449 cites W3134431802 @default.
- W1997992449 cites W83456878 @default.
- W1997992449 doi "https://doi.org/10.1089/jop.2010.0129" @default.
- W1997992449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21790325" @default.
- W1997992449 hasPublicationYear "2012" @default.
- W1997992449 type Work @default.
- W1997992449 sameAs 1997992449 @default.
- W1997992449 citedByCount "16" @default.
- W1997992449 countsByYear W19979924492013 @default.
- W1997992449 countsByYear W19979924492014 @default.
- W1997992449 countsByYear W19979924492015 @default.
- W1997992449 countsByYear W19979924492016 @default.
- W1997992449 countsByYear W19979924492017 @default.
- W1997992449 countsByYear W19979924492019 @default.
- W1997992449 countsByYear W19979924492022 @default.
- W1997992449 countsByYear W19979924492023 @default.
- W1997992449 crossrefType "journal-article" @default.
- W1997992449 hasAuthorship W1997992449A5003065832 @default.
- W1997992449 hasAuthorship W1997992449A5009247381 @default.
- W1997992449 hasAuthorship W1997992449A5044475287 @default.
- W1997992449 hasAuthorship W1997992449A5048313363 @default.
- W1997992449 hasAuthorship W1997992449A5071924058 @default.
- W1997992449 hasAuthorship W1997992449A5074094867 @default.
- W1997992449 hasAuthorship W1997992449A5074581152 @default.
- W1997992449 hasAuthorship W1997992449A5075981348 @default.
- W1997992449 hasAuthorship W1997992449A5087962830 @default.
- W1997992449 hasConcept C118487528 @default.
- W1997992449 hasConcept C126322002 @default.
- W1997992449 hasConcept C134018914 @default.
- W1997992449 hasConcept C169760540 @default.
- W1997992449 hasConcept C196795494 @default.
- W1997992449 hasConcept C204232928 @default.
- W1997992449 hasConcept C2777093970 @default.
- W1997992449 hasConcept C2777397205 @default.
- W1997992449 hasConcept C2778313320 @default.
- W1997992449 hasConcept C2779280383 @default.
- W1997992449 hasConcept C2779829184 @default.
- W1997992449 hasConcept C2780827179 @default.
- W1997992449 hasConcept C555293320 @default.
- W1997992449 hasConcept C71924100 @default.
- W1997992449 hasConcept C86803240 @default.
- W1997992449 hasConceptScore W1997992449C118487528 @default.
- W1997992449 hasConceptScore W1997992449C126322002 @default.
- W1997992449 hasConceptScore W1997992449C134018914 @default.
- W1997992449 hasConceptScore W1997992449C169760540 @default.
- W1997992449 hasConceptScore W1997992449C196795494 @default.