FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998014531> ?p ?o ?g. }

• W1998014531 endingPage "1903" @default.
• W1998014531 startingPage "1903" @default.
• W1998014531 abstract "To study the effect of salvianolate on expression of tumor necrosis factor (TNF)-α and interleukin (IL)-6 mRNA in small intestine of cirrhotic rats.Cirrhosis in rats was induced using CCl4 (0.3 mL/kg). Rats were randomly divided into non-treatment group, low-dose salvianolate (12 mg/kg) treatment group, medium-dose salvianolate (24 mg/kg) treatment group, and high-dose salvianolate (48 mg/kg) treatment group, and treated for 2 wk. Another 10 healthy rats served as a normal control group. Mortality of cirrhotic rats in each group was evaluated after treatment with salvianolate. Serum samples were taken from portal vein for the detection of endotoxin. Morphological changes in tissue samples from the ileocecum were observed under a light microscope. Expression of TNF-α and IL-6 mRNA in the small intestine of rats was analyzed by real-time reverse-transcriptase polymerase chain reaction.The mortality of cirrhotic rats in the non-treatment group was 37.5%. No cirrhotic rat died in the high-dose salvianolate treatment group. The serum endotoxin level was significantly higher in the non-treatment group than in the salvianolate treatment and normal control groups. The intestinal mucosal and villous atrophy, necrosis and shedding of the intestinal mucosal epithelium, observed in the non-treatment group, were reversed in different salvianolate treatment groups. The TNF-α and IL-6 mRNA expression levels in small intestine were significantly lower in different salvianolate treatment groups than in the non-treatment group.Salvianolate can reduce the endotoxin level, ameliorate the injury of intestinal mucosa, and inhibit the expression of TNF-α and IL-6 mRNA in small intestine of cirrhotic rats." @default.
• W1998014531 created "2016-06-24" @default.
• W1998014531 creator A5027406693 @default.
• W1998014531 creator A5051088411 @default.
• W1998014531 creator A5057046498 @default.
• W1998014531 creator A5063127492 @default.
• W1998014531 creator A5066895421 @default.
• W1998014531 creator A5069575896 @default.
• W1998014531 creator A5076845739 @default.
• W1998014531 creator A5087374543 @default.
• W1998014531 date "2011-01-01" @default.
• W1998014531 modified "2023-09-27" @default.
• W1998014531 title "Salvianolate inhibits cytokine gene expression in small intestine of cirrhotic rats" @default.
• W1998014531 cites W1719953756 @default.
• W1998014531 cites W1822961287 @default.
• W1998014531 cites W1976757588 @default.
• W1998014531 cites W1986024575 @default.
• W1998014531 cites W1986050276 @default.
• W1998014531 cites W1991116313 @default.
• W1998014531 cites W1991841736 @default.
• W1998014531 cites W1993564425 @default.
• W1998014531 cites W1998091865 @default.
• W1998014531 cites W2005417810 @default.
• W1998014531 cites W2014234457 @default.
• W1998014531 cites W2014743465 @default.
• W1998014531 cites W2016111787 @default.
• W1998014531 cites W2018853255 @default.
• W1998014531 cites W2028652081 @default.
• W1998014531 cites W2028984739 @default.
• W1998014531 cites W2035580261 @default.
• W1998014531 cites W2054822679 @default.
• W1998014531 cites W2061742805 @default.
• W1998014531 cites W2063558981 @default.
• W1998014531 cites W2065605458 @default.
• W1998014531 cites W2089196154 @default.
• W1998014531 cites W2092047588 @default.
• W1998014531 cites W2101800731 @default.
• W1998014531 cites W2132551814 @default.
• W1998014531 cites W2149266696 @default.
• W1998014531 cites W2153551222 @default.
• W1998014531 cites W2156021051 @default.
• W1998014531 cites W2161789287 @default.
• W1998014531 cites W2162834471 @default.
• W1998014531 cites W2185154752 @default.
• W1998014531 cites W2374395990 @default.
• W1998014531 doi "https://doi.org/10.3748/wjg.v17.i14.1903" @default.
• W1998014531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3080727" @default.
• W1998014531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21528066" @default.
• W1998014531 hasPublicationYear "2011" @default.
• W1998014531 type Work @default.
• W1998014531 sameAs 1998014531 @default.
• W1998014531 citedByCount "11" @default.
• W1998014531 countsByYear W19980145312012 @default.
• W1998014531 countsByYear W19980145312013 @default.
• W1998014531 countsByYear W19980145312014 @default.
• W1998014531 countsByYear W19980145312015 @default.
• W1998014531 countsByYear W19980145312017 @default.
• W1998014531 countsByYear W19980145312018 @default.
• W1998014531 countsByYear W19980145312021 @default.
• W1998014531 crossrefType "journal-article" @default.
• W1998014531 hasAuthorship W1998014531A5027406693 @default.
• W1998014531 hasAuthorship W1998014531A5051088411 @default.
• W1998014531 hasAuthorship W1998014531A5057046498 @default.
• W1998014531 hasAuthorship W1998014531A5063127492 @default.
• W1998014531 hasAuthorship W1998014531A5066895421 @default.
• W1998014531 hasAuthorship W1998014531A5069575896 @default.
• W1998014531 hasAuthorship W1998014531A5076845739 @default.
• W1998014531 hasAuthorship W1998014531A5087374543 @default.
• W1998014531 hasBestOaLocation W19980145311 @default.
• W1998014531 hasConcept C126322002 @default.
• W1998014531 hasConcept C134018914 @default.
• W1998014531 hasConcept C142724271 @default.
• W1998014531 hasConcept C17991360 @default.
• W1998014531 hasConcept C2777214474 @default.
• W1998014531 hasConcept C2777882243 @default.
• W1998014531 hasConcept C3019368612 @default.
• W1998014531 hasConcept C503630168 @default.
• W1998014531 hasConcept C71924100 @default.
• W1998014531 hasConcept C90924648 @default.
• W1998014531 hasConceptScore W1998014531C126322002 @default.
• W1998014531 hasConceptScore W1998014531C134018914 @default.
• W1998014531 hasConceptScore W1998014531C142724271 @default.
• W1998014531 hasConceptScore W1998014531C17991360 @default.
• W1998014531 hasConceptScore W1998014531C2777214474 @default.
• W1998014531 hasConceptScore W1998014531C2777882243 @default.
• W1998014531 hasConceptScore W1998014531C3019368612 @default.
• W1998014531 hasConceptScore W1998014531C503630168 @default.
• W1998014531 hasConceptScore W1998014531C71924100 @default.
• W1998014531 hasConceptScore W1998014531C90924648 @default.
• W1998014531 hasIssue "14" @default.
• W1998014531 hasLocation W19980145311 @default.
• W1998014531 hasLocation W19980145312 @default.
• W1998014531 hasLocation W19980145313 @default.
• W1998014531 hasLocation W19980145314 @default.
• W1998014531 hasOpenAccess W1998014531 @default.
• W1998014531 hasPrimaryLocation W19980145311 @default.
• W1998014531 hasRelatedWork W1966504330 @default.
• W1998014531 hasRelatedWork W1977918131 @default.

• next