Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998018248> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W1998018248 endingPage "43" @default.
- W1998018248 startingPage "43" @default.
- W1998018248 abstract "Background: Rapid bone loss is a frequent finding early after kidney transplantation. Only limited data are available on the bone mineral density (BMD) in long-term kidney transplant recipients. Methods: In 26 kidney transplant recipients (13 men and 13 women, age 45.3 ± 12.3 years), serum biochemical markers of bone metabolism and BMD at the lumbar vertebrae L2-4 were evaluated prospectively in three serial examinations (E1, E2, E3; method: dual-energy X-ray absorptiometry). Examinations were performed at 47 ± 2 months, 59 ± 2 months, and 71 ± 2 months after transplantation. All patients received standard dual or triple immunosuppression including prednisolone. Results: The mean BMD was significantly lower (P < 0.001) than in sex-matched young controls: T-score was −1.43 ± 1.49 (E1), −1.39 ± 1.40 (E2), and −1.44 ± 1.30 (E3). The BMD did not change significantly (Δ BMD, −0.5 ± 5.9%) from E1 to E3. Regression analysis did not show significant associations between Δ BMD and biochemical parameters or prednisolone dosage. No clinically apparent new lumbar vertebral fracture occurred. The mean intact parathyroid hormone was 110.1 ± 97.5 pg/mL (E1), 121 ± 102.7 pg/mL (E2), and 134.5 ± 128.6 pg/mL (E3). Serum creatinine was 1.44 ± 0.45 (128 ± 40) mg/dL (μmol/L) (E1), 1.44 ± 0.47 (127 ± 42) mg/dL (μmol/L) (E2), and 1.45 ± 0.70 (128 ± 62) mg/dL (μmol/L) (E3). Ten patients (38.5%) showed an increase of BMD (+5.7 ± 3.2%) and 15 patients (57.7%) showed a decrease of −4.7 ± 3.2% (P < 0.0001). Both groups were different in T-scores at E1 (−2.29 ± 1 versus −0.88 ± 1.5); intact parathyroid hormone, creatinine, vitamin D levels, and prednisolone dosage were not significantly different. Conclusion: This study shows that lumbar BMD is reduced in long-term kidney transplant recipients. During our 24-month observation period, overall lumbar BMD remained stable. Am J Kidney Dis 40:1066-1074. © 2002 by the National Kidney Foundation, Inc." @default.
- W1998018248 created "2016-06-24" @default.
- W1998018248 creator A5002714970 @default.
- W1998018248 creator A5013022703 @default.
- W1998018248 creator A5025188483 @default.
- W1998018248 date "2000-10-01" @default.
- W1998018248 modified "2023-09-27" @default.
- W1998018248 title "HPLC measurement of pamidronate in urine" @default.
- W1998018248 doi "https://doi.org/10.1016/s8756-3282(00)80148-9" @default.
- W1998018248 hasPublicationYear "2000" @default.
- W1998018248 type Work @default.
- W1998018248 sameAs 1998018248 @default.
- W1998018248 citedByCount "0" @default.
- W1998018248 crossrefType "journal-article" @default.
- W1998018248 hasAuthorship W1998018248A5002714970 @default.
- W1998018248 hasAuthorship W1998018248A5013022703 @default.
- W1998018248 hasAuthorship W1998018248A5025188483 @default.
- W1998018248 hasConcept C126322002 @default.
- W1998018248 hasConcept C126894567 @default.
- W1998018248 hasConcept C134018914 @default.
- W1998018248 hasConcept C170033053 @default.
- W1998018248 hasConcept C2776541429 @default.
- W1998018248 hasConcept C2776715498 @default.
- W1998018248 hasConcept C2776886416 @default.
- W1998018248 hasConcept C2780303639 @default.
- W1998018248 hasConcept C2780306776 @default.
- W1998018248 hasConcept C2911091166 @default.
- W1998018248 hasConcept C71924100 @default.
- W1998018248 hasConcept C90924648 @default.
- W1998018248 hasConceptScore W1998018248C126322002 @default.
- W1998018248 hasConceptScore W1998018248C126894567 @default.
- W1998018248 hasConceptScore W1998018248C134018914 @default.
- W1998018248 hasConceptScore W1998018248C170033053 @default.
- W1998018248 hasConceptScore W1998018248C2776541429 @default.
- W1998018248 hasConceptScore W1998018248C2776715498 @default.
- W1998018248 hasConceptScore W1998018248C2776886416 @default.
- W1998018248 hasConceptScore W1998018248C2780303639 @default.
- W1998018248 hasConceptScore W1998018248C2780306776 @default.
- W1998018248 hasConceptScore W1998018248C2911091166 @default.
- W1998018248 hasConceptScore W1998018248C71924100 @default.
- W1998018248 hasConceptScore W1998018248C90924648 @default.
- W1998018248 hasIssue "4" @default.
- W1998018248 hasLocation W19980182481 @default.
- W1998018248 hasOpenAccess W1998018248 @default.
- W1998018248 hasPrimaryLocation W19980182481 @default.
- W1998018248 hasRelatedWork W1486584413 @default.
- W1998018248 hasRelatedWork W1569816628 @default.
- W1998018248 hasRelatedWork W2016895065 @default.
- W1998018248 hasRelatedWork W2021983387 @default.
- W1998018248 hasRelatedWork W2052365623 @default.
- W1998018248 hasRelatedWork W2081570904 @default.
- W1998018248 hasRelatedWork W2087086071 @default.
- W1998018248 hasRelatedWork W2088891312 @default.
- W1998018248 hasRelatedWork W2589824098 @default.
- W1998018248 hasRelatedWork W2612827772 @default.
- W1998018248 hasVolume "27" @default.
- W1998018248 isParatext "false" @default.
- W1998018248 isRetracted "false" @default.
- W1998018248 magId "1998018248" @default.
- W1998018248 workType "article" @default.