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• W1998018558 abstract "Clinical and biochemial data on 111 consecutive insulin-dependent diabetic children enrolled in a longitudinal prospective study were analyzed to determine if more than one clinical expression of Type I diabetes exists. Use of multivariate statistical methods, including Correspondence Analysis, k-means clustering and RECPAM (RECursive Partition and AMalgamation), show that there are two well differentiated clinical expressions of IDDM each characterized by a cluster. One is characterized by later age, less severe onset, longer symptom duration, less β-cell disappearance after 12 months, more females; the other by earlier age, more sudden and severe onset, DR , earlier disappearance of β-cell function and more males. RECPAM analysis provides further insight into the structure of the two clusters. An other RECPAM tree identifies low, medium and high risk groups of disappearance of β-cell function at 12 months after diagnosis." @default.
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• W1998018558 date "1990-01-01" @default.
• W1998018558 modified "2023-09-23" @default.
• W1998018558 title "Cluster analysis of an insulin-dependent diabetic cohort towards the definition of clinical subtypes" @default.
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• W1998018558 doi "https://doi.org/10.1016/0895-4356(90)90041-m" @default.
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