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• W1998032336 abstract "I read with interest the article by Mojana and associates 1 Mojana F. Cheng L. Bartsch D.U. The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results. Am J Ophthalmol. 2008; 146: 218-227 Abstract Full Text Full Text PDF Scopus (154) Google Scholar on the role of abnormal vitreomacular adhesion in age-related macular degeneration (AMD). Several authors, using ultrasound and optical coherence tomography (OCT), showed that there is a higher rate of vitreomacular adhesion in AMD. 2 Weber-Krause B. Eckardt U. [Incidence of posterior vitreous detachment in eyes with and without age-related macular degeneration An ultrasonic study]. Ophthalmologe. 1996; 93: 660-665 Crossref Scopus (60) Google Scholar , 3 Ondes F. Yilmaz G. Acar M.A. Role of the vitreous in age-related macular degeneration. Jpn J Ophthalmol. 2000; 44: 91-93 Crossref Scopus (75) Google Scholar , 4 Krebs I. Brannath W. Glittenberg C. Posterior vitreomacular adhesion: a potential risk factor for exudative age-related macular degeneration?. Am J Ophthalmol. 2007; 144: 741-746 Abstract Full Text Full Text PDF Scopus (231) Google Scholar Moreover, a high incidence of posterior vitreous attachment was intraoperatively observed by different authors. 5 Lambert H.M. Capone A. Aaberg T.M. et al. Surgical excision of subfoveal neovascular membranes in age-related macular degeneration. Am J Ophthalmol. 1992; 113: 257-262 Abstract Full Text PDF Scopus (246) Google Scholar These data seem to suggest that the vitreous may play a role in the pathogenesis and/or progression of AMD. Different hypothesis have been formulated to explain the role of vitreomacular adhesion in AMD, focusing on both mechanical and biochemical factors. 3 Ondes F. Yilmaz G. Acar M.A. Role of the vitreous in age-related macular degeneration. Jpn J Ophthalmol. 2000; 44: 91-93 Crossref Scopus (75) Google Scholar Based on the hypothesis that a local inflammation induced by AMD may be responsible for focal corresponding adhesion (potentially inducing tractional forces on the retina), the authors wished to determine the frequency of persistent hyaloid adherence to the posterior pole in patients with AMD, using high-resolution spectral-domain OCT. 1 Mojana F. Cheng L. Bartsch D.U. The role of abnormal vitreomacular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results. Am J Ophthalmol. 2008; 146: 218-227 Abstract Full Text Full Text PDF Scopus (154) Google Scholar ReplyAmerican Journal of OphthalmologyVol. 147Issue 2PreviewWe thank Dr Querques for his interest in our article. We appreciate his comments and insights and the issue he has raised. Full-Text PDF" @default.
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• W1998032336 date "2009-02-01" @default.
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• W1998032336 title "Anti-Vascular Endothelial Growth Factor Injection for Exudative Age-related Macular Degeneration in Patients with Vitreo-Macular Traction" @default.
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• W1998032336 doi "https://doi.org/10.1016/j.ajo.2008.10.008" @default.
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