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- W1998096104 abstract "An important pharmacophore in many quinolone antiinfectives is the N1 cyclopropane. By incorporating the cyclopropane into a N1 to C2 bridge, the first quinolone substrate incorporating a spiro fused cyclopropane, 8,9,10-trifluoro-2,3,4,6-tetrahydro-6-oxospiro[1H-benzo[c]quinolizine-1,l-cyclopropane]-5-carboxylic acid, ethyl ester (8), was prepared." @default.
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- W1998096104 date "1988-11-01" @default.
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- W1998096104 title "Synthesis of a novel tricyclic 4-quinolone. Incorporation of a spiro-cyclopropyl group at N1 by bridging to C2" @default.
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- W1998096104 doi "https://doi.org/10.1002/jhet.5570250632" @default.
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