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- W1998135055 abstract "A reduced cerebrospinal fluid (CSF) absorption syndrome has been defined by considering the factors controlling CSF absorption, the pressure gradient between the subarachnoid space and the superior sagittal simus (Pcsf − Pss), and the resistance to flow across the absorptive channels (Rav). The hypothesis is advanced that this represents the underlying defect in the syndrome previously described by various terms including benign intracranial hypertension, pseudotumour cerebri, otitic hydrocephalus and others. The clinical evidence is reviewed and appears to favour an increase in CSF volume secondary to impaired absorption as the cause of the intracranial hypertension in this syndrome. In addition, known aetiological agents have been shown experimentally to cause significant reductions in CSF absorption. Clinically the syndrome may be produced by any factor which increases either Pss or Rav. If this hypothesis is confirmed by further clinical and experimental studies it is suggested that the general term ‘reduced CSF absorption syndrome’ should replace ‘benign intracranial hypertension’ and similar terms." @default.
- W1998135055 created "2016-06-24" @default.
- W1998135055 creator A5027313674 @default.
- W1998135055 date "1975-01-01" @default.
- W1998135055 modified "2023-09-25" @default.
- W1998135055 title "The definition of a reduced CSF absorption syndrome: A reapraisal of benign intracranial heperetension and related conditions" @default.
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- W1998135055 doi "https://doi.org/10.1016/0306-9877(75)90035-3" @default.
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