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- W1998142807 abstract "Acute kidney injury (AKI) is a frequent complication for hospitalized patients and is associated with significantly increased morbidity and mortality. Probably, the delay in diagnosis of AKI resulting from currently available renal function markers such as serum creatinine contributes to the fact that to date, no simple, safe, and effective intervention to prevent or successfully treat AKI in the general patient population has been found. At the time of diagnosis of established AKI, irreversible organ damage might already have occurred. Neutrophil gelatinase-associated lipocalin (NGAL) is a protease-resistant polypeptide, which is released from the distal nephron in response to ischemic, toxic, or inflammatory insult to the kidney. Available data suggest NGAL to be an early and predictive biomarker for AKI. Novel renal biomarkers indicating cellular/tissue damage might guide patient-tailored earlier initiation of nephroprotection or withdrawal of nephrotoxins directed at improvement of outcomes in patients developing AKI." @default.
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- W1998142807 date "2010-01-01" @default.
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- W1998142807 title "Neutrophilen Gelatinase-assoziiertes Lipocalin (NGAL) für akute Nierenschädigung: das renale Troponin? / Neutrophil gelatinase-associated lipocalin for acute kidney injury – the renal troponin?" @default.
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- W1998142807 doi "https://doi.org/10.1515/jlm.2010.012" @default.
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